Table 2

Results on hold-out test set

Any-stage DKD
DKD stages 3–5
DKD stages 4–5
  • Comparison of XGB, RF and the CDC DKD performance includes AUROC, sensitivity, specificity, LR+ and LR‒, and DOR. Prediction of DKD within 5 years following T2DM diagnosis is divided into any-stage DKD, DKD stages 3–5 and DKD stages 4–5.

  • AUROC, area under the receiver operating characteristic; CDC, Centers for Disease Control and Prevention; DKD, diabetic kidney disease; DOR, diagnostic OR; LR+, positive likelihood ratio; LR−, negative likelihood ratio; RF, random forest; T2DM, type 2 diabetes mellitus; XGB, gradient boosted tree.