Incidence rates (IRs, per 10 000 person-years) during 2010–2019 among individuals ≥18 years and incidence rate ratios (IRRs) of hand diagnoses among the population with T1D and T2D, respectively, with the population without DM as reference
Women | Without diabetes | T1D | T2D | ||||||
Diagnosis | Number of events | IR/10 000 | IRR (ref) | Number of events | IR/10 000 | IRR (95% CI) | Number of events | IR/10 000 | IRR (95% CI) |
Carpal tunnel syndrome | 13 086 | 26.1 | 1 | 250 | 95.5 | 3.7 (3.2 to 4.2)* | 1007 | 52.1 | 2.0 (1.9 to 2.1)* |
Ulnar nerve entrapment | 1942 | 3.9 | 1 | 37 | 14.1 | 3.7 (2.6 to 5.0)* | 145 | 7.5 | 1.9 (1.6 to 2.3)* |
Trigger finger | 6253 | 12.5 | 1 | 263 | 100.5 | 8.1 (7.1 to 9.1)* | 813 | 42 | 3.4 (3.1 to 3.6)* |
Dupuytren’s disease | 1648 | 3.3 | 1 | 60 | 22.9 | 7.0 (5.4 to 9.0)* | 182 | 9.4 | 2.9 (2.5 to 3.3)* |
OA of the CMC-1 joint | 3711 | 7.4 | 1 | 37 | 14.1 | 1.9 (1.4 to 2.6)* | 281 | 14.5 | 2.0 (1.7 to 2.2)* |
Men | Without diabetes | T1D | T2D | ||||||
Diagnosis | Number of events | IR/10000 | IRR (ref) | Number of events | IR/10000 | IRR (95% CI) | Number of events | IR/10000 | IRR (95% CI) |
Carpal tunnel syndrome | 6178 | 12.9 | 1 | 188 | 58.1 | 4.5 (3.9 to 5.2)* | 837 | 31.6 | 2.5 (2.3 to 2.6)* |
Ulnar nerve entrapment | 1715 | 3.6 | 1 | 51 | 15.8 | 4.4 (3.3 to 3.8)* | 232 | 8.8 | 2.5 (2.1 to 2.8)* |
Trigger finger | 3662 | 7.6 | 1 | 165 | 51 | 6.7 (5.7 to 7.8)* | 782 | 29.5 | 3.9 (3.6 to 4.2)* |
Dupuytren’s disease | 3952 | 8.2 | 1 | 119 | 36.8 | 4.5 (3.7 to 5.4)* | 590 | 22.3 | 2.7 (2.5 to 3.0)* |
OA of the CMC-1 joint | 1248 | 2.6 | 1 | 14 | 4.3 | 1.7 (0.9 to 2.8)** | 157 | 5.9 | 2.3 (1.9 to 2.7)* |
*P<0.00001, **p=0.055.
CMC, carpometacarpal; DM, diabetes mellitus; OA, osteoarthritis; T1D, type 1 diabetes; T2D, type 2 diabetes.