Pentile | Persistent IAP level (U/g stool) | Participants, n (T2DM, %) | Relative risk (95% CI) | First visit FPG level, mmol/L (mg/dL) | Second visit FPG level, mmol/L (mg/dL) | Percentage increase of FPG level |
Pentile 1 | 0–15.0 | 30 (14, 46.7) | 13.8 (1.87 to 101.3)** | 4.4±0.7 (79.2±12.6) | 6.9±2.5*** (124.2±45.0) | 34.1*** |
Pentile 2 | 15.1–33.0 | 38 (8, 21.1) | 6.9 (0.91 to 52.60) | 4.5±0.8 (81.0±14.4) | 6.1±1.0*** (109.8±18.0) | 25.9* |
Pentile 3 | 33.1–55.0 | 39 (9, 23.1) | 7.0 (0.93 to 52.57) | 4.3±0.8 (77.4±14.4) | 6.0±1.1*** (108.0±19.8) | 25.2** |
Pentile 4 | 55.1–115.0 | 58 (8, 13.8) | 4.8 (0.63 to 36.71) | 4.3±0.8 (77.4±14.4) | 5.6±1.0*** (100.8±18.0) | 23.9* |
Pentile 5 | >115.0 | 34 (1, 2.9) | 1.0 | 4.5±0.7 (81.0±12.6) | 5.5±0.7*** (99.0±12.6) | 17.3 |
All participants, 30–60 years old, were stratified into pentiles based on baseline IAP levels, and then participants with persistent IAP level (during follow-up visit) were identified.
Data are summarized as mean (average)±SD for each variable.
Pentile 5 was the reference pentile for calculating the statistical significance of difference in the percentage of increase of FPG levels (Student’s t-test) as well as evaluating age-adjusted and gender-adjusted relative risk between two pentiles.
*p<0.05, **p<0.01, ***p<0.001.
FPG, fasting plasma glucose; IAP, intestinal alkaline phosphatase; T2DM, type 2 diabetes mellitus.