Cross-sectional beta estimates±SE of the associations of active plasma renin concentration, aldosterone and ARR (per SD) and adipokines (per SD).
| N | Renin | Aldosterone | ARR | |
| Leptin | 2922 | 0.05±0.01*** | 0.05±0.01*** | −0.01±0.01 |
| Retinol-binding protein-4 | 2922 | 0.07±0.02*** | 0.04±0.02* | −0.03±0.02 |
| Adiponectin | 1093 | −0.07±0.03* | −0.05±0.03 | 0.03±0.03 |
| Omentin-1 | 1093 | −0.01±0.04 | 0.00±0.03 | −0.001±0.03 |
| Chemerin | 1702 | 0.04±0.03 | 0.02±0.02 | −0.02±0.03 |
| Progranulin | 1702 | −0.03±0.03 | −0.01±0.03 | 0.02±0.03 |
| Vaspin | 1702 | −0.01±0.03 | 0.07±0.02** | 0.06±0.03* |
*P<0.05; **p<0.01; ***p<0.001; bold print indicates significance after correction for multiple testing using the Bonferroni method (p<0.0024 (0.05 ÷ 21)).
The linear regression models were adjusted for sex, age, BMI, arterial hypertension, eGFR, potassium, use of ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics and calcium channel blockers.
ARR, aldosterone-to-renin-ratio; BMI, body mass index; eGFR, estimated glomerular filtration rate.