Overall sample | Healthy sample* | |||
(n=7272) | (n=2140) | |||
Men | Women | Men | Women | |
(n=3295) | (n=3977) | (n=841) | (n=1299) | |
Age, years | 47±12 | 47±12 | 43±12 | 42±11 |
Systolic blood pressure, mm Hg | 124±15 | 118±18 | 116±10 | 108±11 |
Diastolic blood pressure, mm Hg | 78±9 | 73±10 | 74±8 | 69±8 |
Hypertensive treatment, % | 12% | 11% | N/A | N/A |
Body mass index, kg/m2 | 27.9±4.3 | 26.2±5.6 | 25.4±2.6 | 22.7±2.8 |
Waist circumference, cm | 98.6±11.6 | 87.8±14.7 | 90.9±6.7 | 78.1±6.5 |
Fasting plasma insulin, pmol/L | 28 (22,39) | 26 (21,34) | 25 (19,35) | 23 (18,30) |
2h-insulin, pmol/L‡ | N/A | N/A | 28 (16,45) | 30 (20,45) |
Fasting plasma glucose, mg/dL | 97.0±8.5 | 91.9±8.9 | 94.5±7.3 | 88.3±6.6 |
2h-glucose, mg/dL‡ | N/A | N/A | 96 (81,109) | 92 (79,107) |
Hemoglobin A1C, %† | 5.3±0.6 | 5.3±0.6 | 5.2±0.5 | 5.2±0.5 |
Hemoglobin A1C, mmol/mol† | 34±6.3 | 34±6.5 | 34±4.9 | 33±5.2 |
Total cholesterol, mg/dL | 197±36 | 196±37 | 169±21 | 169±20 |
HDL cholesterol, mg/dL | 46±13 | 60±16 | 50±12 | 63±14 |
Triglycerides, mg/dL | 114 (78,172) | 94 (67,135) | 75 (60,101) | 70 (55,91) |
Dyslipidemia treatment, % | 8% | 4% | N/A | N/A |
C reactive protein, mg/L | 1.0 (0.5,2.2) | 1.3 (0.5,3.5) | 0.7 (0.3,1.4) | 0.7 (0.3,1.7) |
Physical Activity Index | 35.2 (32,40.7) | 34.2 (31,38) | 35.5 (32.5,40.7) | 35.1 (32,39.2) |
Current smokers, % | 17% | 17% | N/A | N/A |
N/A indicates not available/not applicable.
*The healthy sample consists of non-smoking participants free of prevalent diabetes, cardiovascular disease, dyslipidemia, hypertension, and abdominal obesity.
†Hemoglobin A1C was only available in the Offspring cohort and Gen 3, exam 2 participants.
‡2h-insulin and 2h-glucose were only available at Offspring cohort examination cycle 5. Continuous measures are presented as mean±SD or median (Q1, Q3).
HDL, high-density lipoprotein.