Mortality and morbidity rates in the patient groups with and without atrial fibrillation
| Events | Incidence | Unadjusted HR (95% CI) | Adjusted HR (95% CI)† | ||
| n | n/1000 PY | ||||
| Cerebral cardiovascular events | No AF | 300 | 12.93 | 1.00 | 1.00 |
| AF* | 20 | 35.08 | 2.58 (1.64 to 4.08) | 1.65 (1.03 to 2.66) | |
| Stroke | No AF | 160 | 6.67 | 1.00 | 1.00 |
| AF | 11 | 17.93 | 2.48 (1.34 to 4.60) | 1.54 (0.81 to 2.93) | |
| Coronary artery disease | No AF | 155 | 6.52 | 1.00 | 1.00 |
| AF | 11 | 19.02 | 2.96 (1.59 to 5.50) | 1.96 (1.03 to 3.73) | |
| Heart failure | No AF | 51 | 2.09 | 1.00 | 1.00 |
| AF | 12 | 20.03 | 15.11 (7.69 to 29.66) | 5.17 (2.46 to 10.9) | |
| All-cause death | No AF | 437 | 17.80 | 1.00 | 1.00 |
| AF | 31 | 49.34 | 3.66 (2.53 to 5.30) | 1.82 (1.24 to 2.67) | |
| Ischemic stroke | No AF | 110 | 4.56 | 1.00 | 1.00 |
| AF | 8 | 12.96 | 2.64 (1.28 to 5.45) | 1.44 (0.68 to 3.07) | |
| Hemorrhagic events | No AF | 187 | 7.97 | 1.00 | 1.00 |
| AF | 8 | 12.94 | 1.58 (0.78 to 3.23) | 1.34 (0.65 to 2.80) | |
*Number of patients: no AF (2403), AF (127).
†HRs obtained using a Cox proportional hazards model with adjustments for age, sex (men), body mass index (BMI), smoking history (current or past), presence/absence of hypertension and/or dyslipidemia, HbA1c, aspirin use, and duration of diabetes.
AF, atrial fibrillation; PY, person-years.