Table 2

Glucose, insulin and C-peptide concentrations during the OGTT


Malaria negativePeripheral malariaPeripheral+placental malariaP valueP value adjusted
N13–1636–4311–14
Fasting glucose (mmol/L)4.5±0.64.5±0.65.8±0.70.210.29
Glucose 30 min (mmol/L)6.7±1.26.6±1.07.9±1.50.0020.01
Glucose 120 min (mmol/L)6.6 (5.9–6.9)6.1 (5.2-6-8)6.6 (5.4–7.3)0.350.33
Fasting insulin (pmol/L)∞40 (22–57)53 (35–65)64 (30–70)0.110.13
Insulin 30 min (pmol/L)∞318 (174–539)252 (101–414)287 (218–389)0.920.67
Insulin 120 min (pmol/L)∞274 (197–337)252 (165–451)206 (106–333)0.150.12
Fasting C-peptide (pmol/L)∞424 (397–567)443 (374–526)362 (280–670)0.760.96
C-peptide 30 min (pmol/L)∞1562 (1018–1906)1295 (964–1897)1324 (1170–1569)0.970.97
C-peptide 120 min (pmol/L)∞1622 (1360–1081)1666 (1293–2296)1586 (1167–1975)0.700.62
HOMA-IR∞1.13 (0.62–1.81)1.61 (1.10–1.92)1.88 (0.88–2.15)0.180.21
  • ∞P values from log-transformed data due to skewed residuals.

  • HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; OGTT, oral glucose tolerance test.