Table 3

Spearman and partial correlation of variables associated with circulating CTRP3

	Plasma CTRP3		Plasma CTRP3 (age and sex adjusted)
	r	P	r	P
Sex (M/F)	0.002	0.974	–	–
Age (years)	−0.063	0.243	–	–
BMI (kg/m²)	0.104	0.056	−0.115	0.511
SBP (mm Hg)	−0.014	0.795	0.119	0.498
DBP (mm Hg)	0.074	0.168	0.006	0.973
FPG (mmol/L)	0.051	0.531	−0.010	0.952
2hPG (mmol/L)	−0.039	0.632	0.061	0.729
HbA1c (%)	−0.20	<0.001	−0.230	0.041
FINS (mU/L)	−0.052	0.604	−0.081	0.644
TC (mmol/L)	−0.039	0.475	−0.291	0.090
TG (mmol/L)	0.024	0.657	−0.358	0.035
HDL-C (mmol/L)	−0.023	0.68	0.193	0.266
LDL-C (mmol/L)	−0.046	0.398	−0.243	0.159
hsCRP (mg/L)	−0.059	0.454	−0.055	0.756
Urea (mmol/L)	−0.098	0.072	0.055	0.755
Cr (μmoI/L)	0.001	0.989	0.010	0.957
UA (μmoI/L)	0.034	0.527	−0.399	0.018
ALT (U/L)	0.058	0.288	0.026	0.882
AST (U/L)	−0.008	0.879	−0.025	0.887
NSS	−0.174	0.012	−0.322	＜0.001
NDS	−0.147	0.007	−0.158	0.003

Correlation between variables was analyzed by Spearman’s correlation tests and partial correlation tests (adjusted by age and sex).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; Cr, creatinine; CTRP3, C1q/tumor necrosis factor-related protein-3; DBP, diastolic blood pressure; FINS, fasting serum insulin; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; 2hPG, 2-hour post challenge plasma glucose; hsCRP, high-sensitive C reactive protein; LDL-C, low-density lipoprotein cholesterol; NDS, Neuropathy Disability Score; NSS, Neuropathy Symptom Score; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; UA, uric acid.