Table 1

Purpose and resource-based studies of risk for T2DM and related conditions in Latinos of Mexican ancestry

Purpose-driven biobanks
NameLocationPurpose/Study type
Laredo Project22Laredo, TexasEpidemiology of T2DM and cardiovascular risk cohort.
Starr County Study23Starr County, TexasEpidemiology and genetics of T2DM cohort.
Insulin Resistance and Atherosclerosis Study24San Antonio, TexasEpidemiology and characterization of insulin resistance and dyslipidemia cohort.
Genetics of Non-insulin-dependent Diabetes25Multicenter (San Antonio, Texas)Identification of genes causing T2DM. Multiple ethnic group cohort.
San Antonio Family Heart Study26San Antonio, TexasIdentification of genes causing heart disease and related conditions cohort.
Multi-Ethnic Study of Atherosclerosis27MulticenterStudy of genetics, prevalence, and progression of cardiovascular disease in a prospective multiethnic cohort
San Antonio Family Diabetes/Gallbladder Study28San Antonio, TexasIdentification of genes causing T2DM and related diseases cohort.
Veterans Administration Genetic Epidemiology Study29San Antonio, TexasIdentification of genes causing T2DM and related diseases cohort.
Brownsville study30Brownsville, TexasIdentification of biological and social risk factors for T2DM cohort.
Resource-focused biobanks
Arizona Insulin Resistance Registry16Maricopa County, ArizonaResearch registry of individuals of Mexican ancestry at risk of T2DM and cardiometabolic risk willing to participate in future studies (data, plasma, serum, DNA, immortalized white blood cells).
All of US Research Program14Entire US populationDiverse US cohort of >1 million persons to accelerate biomedical research and improve health by connecting biological (genetic), EHR, and SDOH data. Ongoing genetic, epidemiological, and EHR cohort.
Million Vet Program31Population of US VeteransDiverse ongoing cohort of 1 million patients receiving care at Veterans Administration healthcare facilities by connecting EHR to genetic data.
Sangre por Salud biobank17Maricopa County, ArizonaTo expand precision medicine research to include under-represented Latino patients. Biobank embedded in a FQHC that provides infrastructure for precision medicine implementation as well as genetic and clinical information (connected to EHR).
Mil Familias15Santa Barbara, California and environsTo establish an observational cohort of 1000 Latino families with at least one family member with T2DM to understand the impact of genetics, biology, behavior, psychology, and society/environment.
  • Representative examples of purpose-driven studies of T2DM and related conditions such as cardiovascular disease and dyslipidemia among Latinos of Mexican ancestry are listed under the heading ‘Purpose-driven biobanks’. Examples of projects that are designed to provide more comprehensive biobank data and samples to support many investigators are listed under the heading ‘Resource-focused biobanks’. These lists are not intended to be comprehensive.

  • EHR, electronic health record; FQHC, Federally Qualified Health Center; SDOH, social determinants of health; T2DM, type 2 diabetes mellitus.