Purpose and resource-based studies of risk for T2DM and related conditions in Latinos of Mexican ancestry
| Purpose-driven biobanks | ||
| Name | Location | Purpose/Study type |
| Laredo Project22 | Laredo, Texas | Epidemiology of T2DM and cardiovascular risk cohort. |
| Starr County Study23 | Starr County, Texas | Epidemiology and genetics of T2DM cohort. |
| Insulin Resistance and Atherosclerosis Study24 | San Antonio, Texas | Epidemiology and characterization of insulin resistance and dyslipidemia cohort. |
| Genetics of Non-insulin-dependent Diabetes25 | Multicenter (San Antonio, Texas) | Identification of genes causing T2DM. Multiple ethnic group cohort. |
| San Antonio Family Heart Study26 | San Antonio, Texas | Identification of genes causing heart disease and related conditions cohort. |
| Multi-Ethnic Study of Atherosclerosis27 | Multicenter | Study of genetics, prevalence, and progression of cardiovascular disease in a prospective multiethnic cohort |
| San Antonio Family Diabetes/Gallbladder Study28 | San Antonio, Texas | Identification of genes causing T2DM and related diseases cohort. |
| Veterans Administration Genetic Epidemiology Study29 | San Antonio, Texas | Identification of genes causing T2DM and related diseases cohort. |
| Brownsville study30 | Brownsville, Texas | Identification of biological and social risk factors for T2DM cohort. |
| Resource-focused biobanks | ||
| Name | Location | Purpose/Resources |
| Arizona Insulin Resistance Registry16 | Maricopa County, Arizona | Research registry of individuals of Mexican ancestry at risk of T2DM and cardiometabolic risk willing to participate in future studies (data, plasma, serum, DNA, immortalized white blood cells). |
| All of US Research Program14 | Entire US population | Diverse US cohort of >1 million persons to accelerate biomedical research and improve health by connecting biological (genetic), EHR, and SDOH data. Ongoing genetic, epidemiological, and EHR cohort. |
| Million Vet Program31 | Population of US Veterans | Diverse ongoing cohort of 1 million patients receiving care at Veterans Administration healthcare facilities by connecting EHR to genetic data. |
| Sangre por Salud biobank17 | Maricopa County, Arizona | To expand precision medicine research to include under-represented Latino patients. Biobank embedded in a FQHC that provides infrastructure for precision medicine implementation as well as genetic and clinical information (connected to EHR). |
| Mil Familias15 | Santa Barbara, California and environs | To establish an observational cohort of 1000 Latino families with at least one family member with T2DM to understand the impact of genetics, biology, behavior, psychology, and society/environment. |
Representative examples of purpose-driven studies of T2DM and related conditions such as cardiovascular disease and dyslipidemia among Latinos of Mexican ancestry are listed under the heading ‘Purpose-driven biobanks’. Examples of projects that are designed to provide more comprehensive biobank data and samples to support many investigators are listed under the heading ‘Resource-focused biobanks’. These lists are not intended to be comprehensive.
EHR, electronic health record; FQHC, Federally Qualified Health Center; SDOH, social determinants of health; T2DM, type 2 diabetes mellitus.