Renal risk in different treatment strategies
| Intervention | Crude risk (95% CI) | Risk difference (95% CI) | Risk ratio (95% CI) |
| Natural course | 20.0 (19.8 to 21.1)% | (Reference) | (Reference) |
| A1c≥7.0%, within 3 m | 17.2 (14.8 to 20.2)% | −3.1 (−5.4 to −1.4)% | 0.85 (0.73 to 0.97) |
| A1c≥7.0%, within 6 m | 17.7 (15.7 to 20.3)% | −2.5 (−4.6 to −1.2)% | 0.87 (0.77 to 0.98) |
| A1c≥7.0%, within 9 m | 18.1 (16.3 to 20.4)% | −2.1 (−3.9 to −1.0)% | 0.89 (0.80 to 0.99) |
| A1c≥7.0%, within 12 m | 18.5 (16.8 to 20.6)% | −1.8 (−3.3 to −0.93)% | 0.91 (84 to 1.00) |
| A1c≥6.5%, within 3 m | 16.6 (13.7 to 20.0)% | −3.7 (−6.7 to –1.6) | 0.82 (0.68 to 0.97) |
| A1c≥6.5%, within 6 m | 17.2 (14.6 to 20.2)% | −3.1 (−5.6 to −1.4) | 0.85 (0.73 to 0.98) |
| A1c≥6.5%, within 9 m | 17.7 (15.6 to 20.3)% | −2.6 (−4.7 to −1.2) | 0.87 (0.77 to 0.98) |
| A1c≥6.5%, within 12 m | 18.1 (16.2 to 20.4)% | −2.2 (−4.1 to −1.1)% | 0.89 (0.80 to 0.99) |
| A1c≥7.5%, within 3 m | 18.0 (16.2 to 20.4)% | −2.3 (−4.0 to −1.1)% | 0.88 (0.80 to 0.99) |
| A1c≥7.5%, within 6 m | 18.4 (16.8 to 20.5)% | −1.9 (−3.5 to −0.91)% | 0.91 (0.83 to 0.99) |
| A1c≥7.5%, within 9 m | 18.7 (17.3 to 20.6)% | −1.6 (−2.9 to −0.80)% | 0.92 (0.85 to 1.00) |
| A1c≥7.5%, within 12 m | 19.0 (17.7 to 20.7)% | −1.3 (−2.6 to −0.62)% | 0.94 (0.87 to 1.00) |
| Never treated | 20.3 (19.9 to 21.2)% | 0.00 (−0.07 to 0.18)% | 1.00 (1.00 to 1.01) |
The 95% CI was calculated by bootstrapping, without p value output. A 95% CI of a rate that did not cross 0 or a ratio that did not cross 1 was regarded as statistically significant.
A1c, hemoglobin A1c.