Main predictor | Microvascular (n=74 016) | Retinopathy (n=235 580) | Neuropathy (n=222 274) | Nephropathy (n=168 616) |
A1c TIR | ||||
80% to 100% | 1.00 | 1.00 | 1.00 | 1.00 |
60% to <80% | 1.03* (1.00–1.07) | 1.03 (1.00–1.06) | 1.07* (1.04–1.10) | 1.03 (1.00–1.05) |
40% to <60% | 1.02 (0.99–1.05) | 1.04* (1.01–1.07) | 1.05* (1.02–1.08) | 1.05* (1.02–1.08) |
20% to <40% | 1.03* (1.00–1.06) | 1.04* (1.01–1.07) | 1.05* (1.02–1.08) | 1.04* (1.02–1.07) |
0% to <20% | 1.04* (1.02–1.07) | 1.05* (1.02–1.08) | 1.04* (1.01–1.06) | 1.06* (1.04–1.09) |
A1c SD | 1.01 (0.98–1.04) | 0.92* (0.90–0.94) | 0.95* (0.93–0.97) | 1.08* (1.05–1.10) |
A1c mean | 1.09* (1.08–1.11) | 1.17* (1.15–1.18) | 1.10* (1.09–1.11) | 1.08* (1.07–1.09) |
*P<0.05.
A1c, hemoglobin A1c; TIR, time in range.