Multivariable robust regression analyses of total movement volume and measures of glycemic and insulin dynamics
| Men | Women | ||||
| Model 1 | n | β | 95% CI | β | 95% CI |
| Fasting glucose (mmol/L) | 725 | −0.014 | −0.028 to −0.003 | −0.031 | −0.054 to −0.009 |
| 2-hour glucose (mmol/L) | 720 | −0.033 | −0.063 to −0.002 | −0.052 | −0.109 to 0.004 |
| Insulin sensitivity (mgl2/mUmin) | 719 | 0.240 | 0.138 to 0.343 | 0.162 | 0.049 to 0.275 |
| Basal insulin clearance (ng/mIU) | 723 | 0.001 | −0.001 to 0.003 | 0.004 | 0.002 to 0.006 |
| Beta-cell function (mIU/mmol) | 628 | 0.129 | −0.079 to 0.338 | 0.336 | −0.095 to 0.768 |
| Model 2 | |||||
| Fasting glucose (mmol/L) | 726 | −0.014 | −0.027 to −0.0004 | −0.026 | −0.050 to −0.002 |
| 2-hour glucose (mmol/L) | 720 | −0.033 | −0.065 to 0.002 | −0.042 | −0.103 to 0.018 |
| Insulin sensitivity (mgl2/mUmin) | 719 | 0.199 | 0.096 to 0.301 | 0.138 | 0.022 to 0.255 |
| Basal insulin clearance (ng/mIU) | 723 | 0.001 | −0.002 to 0.003 | 0.005 | 0.002 to 0.007 |
| Beta-cell function (mIU/mmol) | 628 | 0.168 | −0.049 to 0.385 | 0.393 | −0.070 to 0.855 |
| Model 3 | |||||
| Fasting glucose (mmol/L) | 690 | −0.006 | −0.019 to 0.008 | −0.019 | −0.041 to 0.008 |
| 2-hour glucose (mmol/L) | 685 | −0.007 | −0.038 to 0.025 | −0.011 | −0.073 to 0.050 |
| Insulin sensitivity (mgl2/mUmin) | 684 | 0.073 | −0.015 to 0.161 | 0.071 | −0.059 to 0.201 |
| Basal insulin clearance (ng/mIU) | 688 | −0.001 | −0.003 to 0.002 | 0.003 | 0.0001 to 0.005 |
| Beta-cell function (mIU/mmol) | 599 | −0.006 | −0.227 to 0.215 | 0.306 | −0.194 to 0.807 |
| Model 4 | |||||
| Fasting glucose (mmol/L) | 690 | −0.004 | −0.018 to 0.009 | −0.013 | −0.037 to 0.011 |
| 2-hour glucose (mmol/L) | 685 | −0.0003 | −0.0311 to 0.0317 | −0.003 | −0.062 to 0.057 |
| Insulin sensitivity (mgl2/mUmin) | 684 | 0.053 | −0.034 to 0.141 | 0.072 | −0.052 to 0.195 |
| Basal insulin clearance (ng/mIU) | 688 | −0.001 | −0.003 to 0.002 | 0.003 | 0.0001 to 0.005 |
| Beta-cell function (mIU/mmol) | 599 | −0.061 | −0.286 to 0.164 | 0.236 | −0.241 to 0.713 |
Beta coefficients represent the difference in the outcomes listed per 1 mg difference in movement volume; bold represents significant associations.
Model 1: included age.
Model 2: included age, HIV status, education, asset category and employment.
Model 3: included age, HIV status, education, asset category and employment and FMI.
Model 4: included age, HIV status, education, asset category and employment, FMI and VAT.
FMI, fat mass index; VAT, visceral adipose tissue.