Table 3

Multivariable linear regression analyses of the relationship between isthmin-1 and log10-transformed urinary albumin:creatinine ratio

β coefficients (95% CI)P value
Model 10.625 (0.316 to 0.933)<0.001
Model 20.683 (0.375 to 0.991)<0.001
Model 30.531 (0.214 to 0.847)<0.01
  • Model 1: unadjusted.

  • Model 2: adjusted for age, gender, BMI, duration of T2DM, HbA1c, and fasting C-peptide.

  • Model 3: adjusted for age, gender, BMI, duration of T2DM, HbA1c, fasting C-peptide, systolic blood pressure, low-density lipoprotein cholesterol, triglyceride, albumin, estimated glomerular filtration rate and ACE inhibitor or angiotensin II antagonist treatment.

  • BMI, body mass index; HbA1c, hemoglobin A1c; T2DM, type 2 diabetes mellitus.