Comparison of maximum C-peptide concentration (nmol/L) mean±SD (range) in 50 children and adolescent with type 1 diabetes after stimulation with a mixed meal test during the 6 year study period in slow and rapid progressor group
| Time | All subjects | Slow progressor | Rapid progressor | P value |
| n=50 | n=30 | n=20 | ||
| Day 0 | 0.37±0.36 | 0.47±0.43 | 0.22±0.12 | 0.008 |
| (0.07–1.86) | (0.12–1.86) | (0.07–0.60) | ||
| 3 months | 0.29±0.18 | 0.32±0.18 | 0.25±0.17 | 0.163 |
| (0.04–0.78) | (0.08–0.75) | (0.04–0.78) | ||
| 9 months | 0.30±0.23 | 0.40±0.25 | 0.15±0.07 | <0.001 |
| (0.04–0.95) | (0.07–0.95) | (0.04–0.29) | ||
| 18 months | 0.15±0.14 | 0.22±0.15 | 0.07±0.05 | <0.001 |
| (0.01–0.63) | (0.04–0.63) | (0.01–0.20) | ||
| 24 months | 0.18±0.20 | 0.27±0.20 | 0.01±0.00 | 0.003 |
| (0.01–0.73) | (0.07–0.73) | (0.01–0.01) | ||
| 30 months | 0.12±0.16 | 0.19±0.17 | 0.01±0.00 | <0.001 |
| (0.01–0.71) | (0.03–0.71) | (0.01–0.01) | ||
| 3 years | 0.05±0.11 | 0.13±0.16 | 0.01±0.00 | 0.048 |
| (0.01–0.56) | (0.01–0.56) | (0.01–0.01) | ||
| 4 years | 0.07±0.10 | 0.11±0.11 | 0.01±0.00 | <0.001 |
| (0.01–0.37) | (0.01–0.37) | (0.01–0.01) | ||
| 5 years | 0.04±0.10 | 0.09±0.14 | 0.01±0.00 | 0.045 |
| (0.01–0.45) | (0.01–0.45) | (0.01–0.01) | ||
| 6 years | 0.04±0.07 | 0.07±0.09 | 0.01±0.00 | 0.007 |
| (0.01–0.28) | (0.01–0.28) | (0.01–0.01) |
P values <0.05 were considered statistically significant.