Table 2

Characteristics of 50 children and adolescent at diagnosis of type 1 diagnosis (mean±SD)

All subjects mean±SD n=50Slow progressor mean±SD n=30Rapid progressor mean±SD n=20P value
Year of diagnosis2009±32008±32010±30.108
Age at diagnosis (years)10.6±2.511.1±2.610.0±2.30.132
HbA1c (mmol/mol)99±2696±29104±190.250
HbA1c (%)11.2±4.510.9±4.811.7±3.90.250
Blood glucose (mmol/L)28.8±14.925.4±9.433.6±19.70.068
Ketoacidosis (pH<7.0)7/482/285/200.084
GADA detectable33/4218/2515/170.208
IA-2A detectable32/4217/2515/170.131
GADA and IA-2A29/4214/2515/170.027
HLA-risk profile29/3916/2413/150.164
  • Differences in the slow versus rapid progressor group. P value <0.05 was considered as statistically significant.

  • BMISDS, body mass index SD scores; GADA, glutamic acid decarboxylase antibodies; IA-2A, islet antigen-2 antibodies.