Comparison of blood glucose levels among different genotypes of candidate SNPs
| SNPs | OGTT | Genotypes | F values | P values | ||
| Blood sugar levels | AA | AB | BB | |||
| rs10440833 | FPG | 4.87±0.73 | 4.79±0.80 | 4.71±0.72 | 2.879 | 0.057 |
| 1h-OGTT | 9.63±2.02* | 9.28±2.16 | 9.07±2.11 | 3.988 | 0.019 | |
| 2h-OGTT | 8.49±1.89* | 8.16±1.97 | 7.91±1.86 | 5.611 | 0.004 | |
| rs10946398 | FPG | 4.83±0.73 | 4.81±0.80 | 4.73±0.83 | 0.72 | 0.487 |
| 1h-OGTT | 9.54±2.02 | 9.28±2.18 | 9.13±2.17 | 1.407 | 0.245 | |
| 2h-OGTT | 8.45±1.91* | 8.16±1.95 | 7.97±1.99 | 3.012 | 0.05 | |
| rs4712523 | FPG | 4.83±0.73 | 4.81±0.80 | 4.73±0.84 | 0.704 | 0.495 |
| 1h-OGTT | 9.54±2.03 | 9.30±2.17 | 9.11±2.18 | 1.926 | 0.146 | |
| 2h-OGTT | 8.47±1.90* | 8.17±1.95 | 7.96±2.00 | 3.726 | 0.024 | |
| rs4712524 | FPG | 4.83±0.73 | 4.81±0.80 | 4.73±0.83 | 0.81 | 0.445 |
| 1h-OGTT | 9.54±2.01 | 9.29±2.17 | 9.13±2.16 | 1.592 | 0.204 | |
| 2h-OGTT | 8.45±1.90* | 8.16±1.95 | 7.98±2.00 | 3.005 | 0.05 | |
| rs7754840 | FPG | 4.84±0.73 | 4.81±0.80 | 4.73±0.83 | 0.671 | 0.512 |
| 1h-OGTT | 9.58±2.00 | 9.26±2.18 | 9.13±2.17 | 1.827 | 0.161 | |
| 2h-OGTT | 8.46±1.87* | 8.14±1.96 | 7.97±2.00 | 3.117 | 0.045 | |
A: risk allele; B: major allele.
*The blood glucose level of AA or AB genotype was compared with that of BB genotype, p<0.05, and the difference was statistically significant.
OGTT, oral glucose tolerance test; SNP, single nucleotide polymorphism.