Characteristic/measure | Correlation | ||
Total score (rt) | Worry subscale (rw) | Behavior subscale (rb) | |
Female | 0.23* | 0.24* | 0.11* |
Age (years) | −0.09* | −0.08* | −0.07 |
Duration of T1D (years) | −0.17* | −0.17* | −0.11* |
Number of comorbidities | 0.19* | 0.17* | 0.18* |
MDI versus pump | −0.08 | −0.05 | −0.11* |
Glucometer use (vs CGM use) | 0.02 | 0.03 | 0.01 |
Self-reported A1c (%) | 0.21* | 0.15* | 0.27* |
Gold score | 0.12* | 0.13* | 0.03 |
Number of mild hypoglycemia per week | −0.02 | −0.02 | −0.01 |
Number of moderate hypoglycemia per week | 0.01 | 0.02 | −0.02 |
Number of severe hypoglycemia in the past 12 months | 0.09* | 0.08 | 0.07 |
Number of lifetime severe hypoglycemia | 0.08 | 0.09* | 0.03 |
BMI (kg/m2) | 0.09* | 0.06 | 0.13* |
Comfortable blood glucose range—low | 0.15* | 0.12* | 0.16* |
Comfortable blood glucose range—high | 0.05 | 0.00 | 0.15* |
FoH worry score | 0.95* | – | – |
FoH behavior score | 0.74* | 0.49* | – |
General anxiety (GAD-7) | 0.37* | 0.32* | 0.33* |
Depression (PHQ-8) | 0.37* | 0.31* | 0.35* |
HFS total score | 0.78* | 0.72* | 0.61* |
HFS worry score | 0.74* | 0.75* | 0.45* |
HFS behavior score | 0.65* | 0.52* | 0.69* |
Gold score measures impaired awareness of hypoglycemia (responses range from ‘Always aware (1)’ to ‘Never aware (7)’). GAD-7 is a 7-item anxiety scale developed to diagnose generalized anxiety disorder. PHQ-8 is an outcome measure that is used both as a diagnostic and severity measure for depressive disorders in clinical studies. HFS-II (short form) is an 11-item patient-reported outcome measure that assesses adults’ behavior (5 items) and worry (6 items) related to hypoglycemia in the past 6 months.
*P<0.05.
A1c, glycated hemoglobin; BMI, body mass index; CGM, continuous glucose monitoring; FoH, fear of hypoglycemia; GAD-7, 7-Item Generalized Anxiety Disorder Scale; HFS-II, Hypoglycemia Fear Survey-II; MDI, multiple daily injections; PHQ-8, 8-Item Patient Health Questionnaire; rb, correlation coefficient behavior score; rt, correlation coefficient total score; rw, correlation coefficient worry score; T1D, type 1 diabetes.