Most parsimonious Cox model of independent predictors of all-cause mortality (upper panel), and Cox and competing risk (Fine and Gray) models of independent predictors of death from CVD (lower panel) in FDS1 participants with type 1 diabetes with age as the timeline
| Baseline variable | HR (95% CI) | P value | Subdistribution HR (95% CI) | P value |
| All-cause mortality | ||||
| Age at diabetes diagnosis quintiles* | ||||
| 1st, 3rd–5th | 1.00 (reference) | |||
| 2nd | 3.57 (1.61 to 7.96) | 0.002 | ||
| HbA1c (increase of 1% (11 mmol/L)) | 1.37 (1.18 to 1.60) | <0.001 | ||
| Ln(urinary albumin:creatinine ratio (mg/mmol))† | 1.21 (1.04 to 1.40) | 0.011 | ||
| Any retinopathy | 2.40 (1.31 to 4.39) | 0.005 | ||
| CVD mortality | ||||
| Age at diabetes diagnosis quintiles*: | ||||
| 1st, 3rd–5th | 1.00 (reference) | |||
| 2nd | 6.71 (2.08 to 21.67) | 0.001 | ||
| ABSI‡ (increase of 0.001 m11/6/kg2/3) | 1.14 (1.03 to 1.25) | 0.008 | ||
| HbA1c (increase of 1% (11 mmol/mol)) | 1.43 (1.11 to 1.86) | 0.006 | ||
| Ln(urinary albumin:creatinine (mg/mmol))† | 1.42 (1.19 to 1.71) | <0.001 | ||
| History of ischemic heart disease | 3.02 (1.32 to 6.90) | 0.009 |
*Age at diabetes diagnosis (years) quintiles: first, 1.6–17.5; second,17.6–26.82; third, 26.83–32.1; fourth, 32.2–38.26; and fifth, 38.27–75.2.
†A 2.72-fold increase in urinary albumin:creatinine ratio corresponds to an increased risk of one in ln(urinary albumin:creatinine ratio).
‡ABSI=m11/6 /kg2/3.
ABSI, A Body Shape Index; CVD, cardiovascular disease.