Table 4

Pooled baseline characteristics of 93 participants with T1D matched 1:1 on age and sex with 93 participants with type 2 diabetes from the Fremantle Diabetes Study Phase I by all-cause mortality

Alive on 31 December 2017Deceased by 31 December 2017P value
Number (%)96 (51.6)90 (48.4)
Age (years)42.6±10.554.9±12.1<0.001
Male (%)53.167.80.051
Ethnic background (%)0.566
Anglo-Celt58.361.1
Southern European12.518.9
Other European9.46.7
Asian3.13.3
Aboriginal3.13.3
Mixed/other13.56.7
Not fluent in English (%)8.311.10.622
Educated beyond primary school level (%)87.182.00.413
Married/de facto relationship (%)65.668.90.643
Smoking status (%)0.062
Never46.230.0
Ex-smoker31.244.4
Current22.625.6
Alcohol consumption (standard drinks/day)0.1 (0–0.8)0 (0–0.3)0.273
Any exercise in past 2 weeks (%)79.874.40.483
Body mass index (kg/m2)28.9±6.229.9±6.60.304
ABSI (m11/6/kg2/3)0.078±0.0060.082±0.005<0.001
Overweight/obese by waist circumference (%)*44.852.90.302
T1D (%)41.758.90.027
Age at diagnosis (years)36.5±11.240.5±14.10.033
Diabetes duration (years)4.2 (0.8–9.0)11.5 (4.9–22.0)<0.001
Fasting serum glucose (mmol/L)9.1 (6.6–14.1)10.2 (7.9–14.1)0.084
HbA1c (%)7.8 (6.5–8.6)9.0 (7.7–10.2)<0.001
HbA1c (mmol/mol)62 (48–70)75 (61–88)<0.001
Diabetes treatment (%)<0.001
Diet28.07.8
 OGLMs29.026.7
Insulin±OGLM43.065.6
Systolic blood pressure (mm Hg)131±18149±26<0.001
Diastolic blood pressure (mm Hg)79±1082±120.027
On blood pressure-lowering medication (%)18.844.4<0.001
Heart rate (beats/min)69±1174±150.018
Total serum cholesterol (mmol/L)5.3±0.95.5±1.80.281
Serum HDL cholesterol (mmol/L)1.10±0.401.04±0.400.359
Serum triglycerides (mmol/L)1.7 (0.8–3.4)1.9 (0.8–4.2)0.239
Lipid-lowering medication (%)4.213.30.035
Aspirin use (%)3.118.00.001
eGFR (CKD-EPI) category (%)0.001
≥90 mL/min/1.73m252.134.1
60–89 mL/min/1.73m244.746.6
45–59 mL/min/1.73m23.214.8
<45 mL/min/1.73m204.5
Urinary albumin:creatinine ratio (mg/mmol)1.3 (0.4–4.5)5.4 (0.9–33.4)<0.001
Any retinopathy (%)12.840.2<0.001
Ischemic heart disease (%)7.331.1<0.001
Heart failure (%)08.90.003
Cerebrovascular disease (%)2.113.30.004
Distal sensory polyneuropathy (8-point) (%)10.440.0<0.001
Peripheral arterial disease (%)15.828.40.049
Charslon Comorbidity Index categories (%)0.027
085.472.2
1 or 213.520.0
≥31.07.8
  • *Waist circumference ≥94.0 cm (men), ≥80.0 cm (women).

  • eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; OGLM, oral glucose-lowering medication; T1D, type 1 diabetes.