Age, ethnicity, and sex-adjusted | Multivariable-adjusted† | |||||||
OR | 95% CI | P value | OR | 95% CI | P value | |||
Ethnicity | ||||||||
Chinese | Ref. | Ref. | Ref. | <0.001 | Ref. | Ref. | Ref. | 0.008 |
Malays | 2.08 | 1.69 | 2.56 | 1.17 | 0.89 | 1.54 | ||
Indians | 2.22 | 1.80 | 2.74 | 1.51 | 1.16 | 1.96 | ||
Education level | ||||||||
Primary or less | Ref. | Ref. | Ref. | 0.039 | Ref. | Ref. | Ref. | 0.256 |
Lower secondary | 1.00 | 0.82 | 1.22 | 1.17 | 0.92 | 1.50 | ||
Higher secondary | 0.71 | 0.52 | 0.96 | 0.87 | 0.59 | 1.30 | ||
College | 0.74 | 0.52 | 1.06 | 1.16 | 0.74 | 1.82 | ||
Household income (SGD/month) | ||||||||
<$2000 | Ref. | Ref. | Ref. | 0.282 | Ref. | Ref. | Ref. | 0.645 |
$2000–$3999 | 0.91 | 0.72 | 1.16 | 0.88 | 0.68 | 1.14 | ||
$4000–$5999 | 0.85 | 0.65 | 1.12 | 0.99 | 0.73 | 1.33 | ||
>$6000 | 0.61 | 0.44 | 0.83 | 0.84 | 0.59 | 1.21 | ||
BMI | 1.83 | 1.69 | 2.00 | <0.001 | 1.81 | 1.65 | 2.00 | <0.001 |
BMI-adjusted waist | 1.40 | 1.26 | 1.56 | <0.001 | 1.50 | 1.32 | 1.70 | <0.001 |
Systolic blood pressure | 1.49 | 1.37 | 1.63 | <0.001 | 1.32 | 1.19 | 1.47 | <0.001 |
HOMA-IR | 1.49 | 1.36 | 1.63 | <0.001 | 1.22 | 1.12 | 1.33 | <0.001 |
HOMA-B | 0.89 | 0.78 | 1.02 | 0.104 | 0.82 | 0.70 | 0.97 | <0.001 |
Adiponectin | 0.52 | 0.46 | 0.58 | <0.001 | 0.53 | 0.46 | 0.61 | <0.001 |
C reactive protein | 1.25 | 1.18 | 1.33 | <0.001 | 1.13 | 1.05 | 1.23 | <0.001 |
Triglycerides | 1.47 | 1.37 | 1.58 | <0.001 | 1.32 | 1.22 | 1.43 | <0.001 |
HDL-cholesterol | 0.63 | 0.56 | 0.70 | <0.001 | 0.78 | 0.68 | 0.89 | <0.001 |
*Estimates are ORs (95% CIs) per SD increase for the continuous variables.
†Further adjusted for education level (four categories), household income (four categories), cigarette smoking, physical activity, and BMI. For HOMA-B, models 1 and 2 also included HOMA-IR.
BMI, body mass index; HDL, high-density lipoprotein; HOMA-B and HOMA-IR, homeostasis model assessment of beta-cell function and insulin resistance, respectively; Ref., reference; SGD, Singapore dollar.