OR of obesity risk according to the FTO rs9939609 genotype in Koreans
| Without obesity, n (%) | With obesity, n (%) | OR (95% CI) | |||
| Crude model | Adjusted model* | ||||
| Males | TT | 1408 (77.6) | 1006 (75.9) | Ref | Ref |
| TA+AA | 406 (22.4) | 319 (24.1) | 1.100 (0.930 to 1.300) | 1.084 (0.914 to 1.285) | |
| P value | 0.266 | 0.356 | |||
| <48 years† | |||||
| TT | 635 (56.1) | 496 (43.9) | Ref | Ref | |
| TA+AA | 184 (50.3) | 182 (49.7) | 1.266 (1.000 to 1.604) | 1.256 (0.990 to 1.594) | |
| P value | 0.050 | 0.061 | |||
| ≥48 years | |||||
| TT | 773 (60.2) | 510 (39.8) | Ref | Ref | |
| TA+AA | 222 (61.8) | 137 (38.2) | 0.935 (0.735 to 1.190) | 0.932 (0.729 to 1.161) | |
| P value | 0.586 | 0.571 | |||
| Females | TT | 1456 (78.7) | 1099 (74.0) | Ref | Ref |
| TA+AA | 393 (21.3) | 387 (26.0) | 1.305 (1.111 to 1.532) | 1.281 (1.089 to 1.507) | |
| P value | 0.001 | 0.003 | |||
| <50 years† | |||||
| TT | 795 (63.8) | 451 (36.2) | Ref | Ref | |
| TA+AA | 205 (55.0) | 168 (45.0) | 1.359 (1.071 to 1.723) | 1.374 (1.081 to 1.748) | |
| P value | 0.011 | 0.010 | |||
| ≥50 years | |||||
| TT | 661 (50.0) | 648 (50.0) | Ref | Ref | |
| TA+AA | 188 (45.1) | 229 (54.9) | 1.243 (0.996 to 1.550) | 1.228 (0.983 to 1.533) | |
| P value | 0.054 | 0.070 | |||
*Adjusted models considered residence area, age, alcohol consumption, smoking status, educational level, physical activity, cohabitation, and total energy.
†Median age of each sex group.
n, number of subjects; Ref, reference.