Table 1

Baseline characteristics according to baseline age

Baseline age <60 yearsBaseline age ≥60 years
ILIDSEILIDSE
Number1480145010901125
Sex
 Women948 (64.1)938 (64.7)578 (53.0)599 (53.2)
 Men532 (35.9)512 (35.3)512 (47.0)526 (46.8)
Age (years)53.9 (4.1)54.0 (4.1)64.9 (4.0)65.2 (4.0)
Race/ethnic group
 White855 (57.8)864 (59.6)766 (70.3)767 (68.2)
 African American242 (16.4)247 (17.0)158 (14.5)157 (14.0)
 Hispanic242 (16.4)205 (14.1)98 (9.0)135 (12.0)
 American Indian89 (6.0)96 (6.6)41 (3.8)32 (2.8)
 Other or mixed*51 (3.4)38 (2.6)27 (2.5)34 (3.0)
Duration of diabetes (years)6.0 (6.0)6.0 (5.4)7.8 (7.3)7.9 (7.4)
History of cardiovascular disease135 (9.1)120 (8.3)230 (21.1)227 (20.2)
Weight (kg)102.2 (20.6)102.8 (19.5)98.3 (18.1)98.4 (17.7)
BMI (kg/m2)36.6 (6.3)36.8 (6.0)34.9 (5.5)34.9 (5.2)
Waist circumference (cm)114.3 (15.2)114.6 (13.9)113.0 (13.0)113.4 (13.1)
HbA1c
 Per cent7.3 (1.2)7.4 (1.3)7.2 (1.0)7.2 (1.1)
 IFCC units (mmol/L)56 (13.1)57 (14.2)55 (10.9)55 (12.0)
Systolic blood pressure (mm Hg)126.3 (16.2)128.2 (16.7)130.7 (18.2)131.1 (17.3)
Diastolic blood pressure (mm Hg)70.9 (9.5)71.3 (9.5)68.6 (9.5)69.2 (9.6)
Urine ACR (mg/g), median8.6 (5.2–18.2)8.5 (5.2–17.8)8.6 (5.2–18.3)9.4 (5.5–21.1)
Urine ACR ≥300 mg/g41 (2.8)29 (2.1)35 (3.3)38 (3.5)
Serum creatinine (mg/dL)0.8 (0.2)0.8 (0.2)0.9 (0.2)0.9 (0.2)
eGFR (mL/min/1.73 m2), median101 (87–107)102 (88–106)90 (76–98)91 (75–98)
eGFR <45 mL/min/1.73 m24 (0.3)3 (0.2)8 (0.7)6 (0.5)
Insulin treatment220 (15.4)224 (16.0)165 (15.6)186 (17.2)
Kidney disease category‡
 Normal or low risk1196 (82.9)1163 (82.5)821 (78.3)821 (75.9)
 Moderate risk196 (13.6)213 (15.1)174 (16.6)203 (18.8)
 High risk47 (3.3)30 (2.1)43 (4.1)52 (4.8)
 Very high risk4 (0.3)4 (0.3)10 (1.0)5 (0.5)
  • Statistics are number (%), mean (SD), or median (IQR).

  • All baseline variables differed significantly (p<0.05) by age except for ACR and insulin treatment.

  • *Other consists of Asian Americans, Pacific Islanders, those reporting a race other than the investigator-specified categories, or those who did not answer. Participants who reported belonging to more than one race were classed as mixed race.

  • †Includes those with history of renal replacement therapy regardless of laboratory results.

  • ‡From the Kidney Disease Improving Global Outcomes classification.9

  • ACR, albumin-to-creatinine ratio; BMI, body mass index; DSE, diabetes support and education; eGFR, estimated glomerular filtration rate; IFCC, International Federation of Clinical Chemistry and Laboratory Medicine; ILI, intensive lifestyle intervention.