Distribution of CRP by sociodemographic characteristics and CVD risk factors among adolescents aged 12–19 years, NHANES 2015–2020
| hs-CRP | ||||
| Low risk (<1.0 mg/L) (N=1670) | Average risk (1.0–3.0 mg/L) (N=594) | High risk (>3.0 mg/L) (N=429) | χ2, p value | |
| Total | 62.1 (1.5) | 22.6 (1.1) | 15.3 (1.0) | |
| Age (years) | <0.001 | |||
| 12–15 | 68.1 (1.8) | 20.3 (1.5) | 11.7 (1.2) | |
| 16–19 | 55.8 (2.1) | 25.1 (1.7) | 19.1 (1.5) | |
| Sex | 0.023 | |||
| Male | 65.3 (2.3) | 22.2 (1.8) | 12.5 (1.2) | |
| Female | 58.6 (1.9) | 23.0 (1.4) | 18.4 (1.6) | |
| Race and ethnicity | 0.004 | |||
| Non-Hispanic white | 63.7 (2.4) | 21.9 (1.6) | 14.4 (1.8) | |
| Non-Hispanic black | 64.8 (2.2) | 18.2 (1.5) | 17.0 (1.7) | |
| Hispanic | 57.5 (1.9) | 26.9 (1.6) | 15.6 (1.5) | |
| Non-Hispanic Asian | 67.7 (3.0) | 21.3 (2.9) | 11.0 (1.7) | |
| Poverty income ratio | 0.003 | |||
| <1.0 | 53.4 (2.5) | 26.5 (2.1) | 20.2 (1.7) | |
| 1.0–2.0 | 60.9 (2.8) | 24.4 (2.2) | 14.7 (1.6) | |
| ≥2.0 | 66.5 (2.1) | 19.5 (1.7) | 14.0 (1.4) | |
| Food security | 0.009 | |||
| Marginal/low | 57.6 (2.0) | 26.0 (1.6) | 16.4 (1.0) | |
| Secure | 64.9 (1.7) | 20.6 (1.4) | 14.5 (1.4) | |
| Adiposity | <0.001 | |||
| Underweight | 93.0 (3.6) | 1.3 (1.1) | 5.7 (3.1) | |
| Normal weight | 77.7 (1.6) | 14.8 (1.2) | 7.5 (1.0) | |
| Overweight | 57.2 (3.2) | 30.1 (3.0) | 12.7 (2.0) | |
| Obese | 25.6 (2.5) | 37.3 (2.4) | 37.1 (2.1) | |
| A1c* | ||||
| <5.7 (<39 mmol/mol) | 63.4 (1.5) | 22.4 (1.2) | 14.2 (1.0) | <0.001 |
| ≥5.7 (≥39 mmol/mol) | 45.5 (3.4) | 25.5 (3.2) | 29.0 (3.9) | |
| Fasting plasma glucose (mg/dL)† | ||||
| <100 | 61.8 (2.6) | 22.7 (1.9) | 15.5 (2.1) | 0.946 |
| ≥100 | 61.1 (3.7) | 22.5 (3.8) | 16.4 (2.3) | |
| Hypertension | 0.121 | |||
| Yes | 53.0 (9.9) | 17.7 (6.1)1 | 29.3 (8.3) | |
| No | 62.1 (1.6) | 22.7 (1.2) | 15.3 (1.0) | |
| Hyperlipidemia | ||||
| High total cholesterol | <0.001 | |||
| Yes | 53.8 (2.6) | 26.0 (2.1) | 20.2 (2.1) | |
| No | 65.1 (1.4) | 21.4 (1.0) | 13.5 (1.0) | |
| Low HDL | <0.001 | |||
| Yes | 49.7 (2.5) | 26.5 (1.7) | 23.8 (1.8) | |
| No | 67.8 (1.5) | 20.9 (1.3) | 11.3 (1.1) | |
| High LDL | <0.001 | |||
| Yes | 44.7 (4.8) | 32.8 (4.8) | 22.5 (4.5) | |
| No | 64.9 (2.6) | 20.7 (1.8) | 14.5 (1.8) | |
| High triglyceride | 0.003 | |||
| Yes | 37.6 (5.7) | 45.9 (6.9) | 16.4 (3.7) | |
| No | 63.5 (2.8) | 20.7 (2.1) | 15.7 (1.7) | |
*Due to the small sample size for A1c≥6.5% (≥48 mmol/mol) (0.5% total sample, see Table 1), the distribution of CRP among those with A1c≥6.5% (≥48 mmol/mol) could not be determined.
†Due to the small sample size for FPG≥126mg/dL (0.6% total sample, see Table 1), the distribution of CRP among those with FPG≥126mg/dL could not be determined.
CRP, C reactive protein; CVD, cardiovascular disease; FPG, fasting plasma glucose; HDL, high-density lipoprotein; hs-CRP, high-sensitivity CRP; LDL, low-density lipoprotein; NHANES, National Health and Nutrition Examination Survey.