Spearman’s correlation r and linear regression analysis of variables associated with circulating ISM1 levels in the studied subjects
| Variable | Spearman’s correlation | Multiple | |||
| r | P value | B | P value | 95% CI | |
| Age | −0.079 | 0.327 | — | — | — |
| BMI | 0.265 | <0.001 | 0.030 | 0.036 | (0.002，0.058) |
| SBP | 0.032 | 0.69 | — | — | — |
| DBP | 0.013 | 0.874 | — | — | — |
| UA | 0.215 | 0.007 | — | — | — |
| ALT | 0.208 | 0.009 | 0.003 | 0.075 | (−0.000，0.006) |
| AST | 0.165 | 0.04 | — | — | — |
| TG | 0.115 | 0.151 | — | — | — |
| TC | 0.163 | 0.043 | 0.118 | 0.008 | (0.032，0.204) |
| HDL | −0.172 | 0.032 | −0.345 | 0.03 | (−0.653，−0.037) |
| LDL | 0.183 | 0.022 | — | — | — |
| WBCs | 0.134 | 0.096 | — | — | — |
| HBA1c | 0.09 | 0.265 | — | — | — |
| FBG | 0.123 | 0.125 | — | — | — |
| FINS | 0.18 | 0.024 | — | — | — |
| HOMA-IR | 0.191 | 0.018 | — | — | — |
In stepwise regression analysis, the values included for analysis were age, BMI, SBP, DBP, albumin, ALT, AST, HbA1c, UA, TG, TC, HDL-C, WBC, FINS, HOMA-IR.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; FBG, fasting blood glucose; Fins, fasting insulin; HbA1c, glycosylated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides; UA, uric acid; WBCs, white blood cells.