Standard diet | Keto diet | Keto diet plus esters | |||||||
Before | After | P value | Before | After | P value | Before | After | P value | |
∆CPEP0-120 (ng/mL) | 8.93±0.95 | 10.89±1.80 | p=0.351 | 6.71±1.05 | 11.44±1.92 | p=0.045 | 6.14±1.16 | 8.47±1.43 | p=0.221 |
∆CPEP0-120/∆G0-120 | 0.04±0.00 | 0.05±0.01 | p=0.211 | 0.03±0.00 | 0.04±0.01 | p=0.134 | 0.03±0.01 | 0.04±0.01 | p=0.344 |
Matsuda Index | 2.56±0.59 | 2.31±0.67 | p=0.786 | 2.58±0.35 | 1.68±0.25 | p=0.053 | 2.15±0.22 | 2.37±0.5 | p=0.685 |
DI=(∆CPEP/∆G)0-120 /IR × 100 | 1.25±0.0028 | 2.48±0.0263 | p=0.226 | 0.92±0.14 | 1.17±0.20 | p=0.320 | 0.98±0.20 | 1.28±0.27 | p=0.386 |
HOMA-IR = FI (mU/L) × FPG (mg/dL)/405 | 6±1.2 | 7±1.5 | p=0.714 | 5±0.6 | 8±1.5 | p=0.085 | 7±2.1 | 7±1.8 | p=0.930 |
Values represent the mean±SEM *A value of p<0.05 is considered significantly different from paired t-test in each diet group; standard diet (n=8), keto diet (n=10) and keto diet plus esters (n=11).
DI, Disposition Index; FI, Fasting Insulin; FPG, fasting plasma glucose; HOMA-IR, Homeostasis Model Assessment of Insulin Resistance ; IR, insulin resistance.