Table 4

Effect of standard diet, keto diet, and keto diet plus keto esters on parameters of insulin secretion

Standard dietKeto dietKeto diet plus esters
BeforeAfterP valueBeforeAfterP valueBeforeAfterP value
∆CPEP0-120 (ng/mL)8.93±0.9510.89±1.80p=0.3516.71±1.0511.44±1.92p=0.0456.14±1.168.47±1.43p=0.221
∆CPEP0-120/∆G0-1200.04±0.000.05±0.01p=0.2110.03±0.000.04±0.01p=0.1340.03±0.010.04±0.01p=0.344
Matsuda Index2.56±0.592.31±0.67p=0.7862.58±0.351.68±0.25p=0.0532.15±0.222.37±0.5p=0.685
DI=(∆CPEP/∆G)0-120 /IR × 1001.25±0.00282.48±0.0263p=0.2260.92±0.141.17±0.20p=0.3200.98±0.201.28±0.27p=0.386
HOMA-IR = FI (mU/L) × FPG (mg/dL)/4056±1.27±1.5p=0.7145±0.68±1.5p=0.0857±2.17±1.8p=0.930
  • Values represent the mean±SEM *A value of p<0.05 is considered significantly different from paired t-test in each diet group; standard diet (n=8), keto diet (n=10) and keto diet plus esters (n=11).

  • DI, Disposition Index; FI, Fasting Insulin; FPG, fasting plasma glucose; HOMA-IR, Homeostasis Model Assessment of Insulin Resistance ; IR, insulin resistance.