Abstract
Diabetic muscle infarction (DMI) is a rare, painful and potentially serious complication in patients with poorly controlled diabetes mellitus and frequently misdiagnosed clinically as abscess, neoplasm, or myositis. A 36-year-old diabetic woman referred to our clinic with severe pain in the left antero-medial thigh. She had a 15-year history of Type 2 diabetes mellitus (DM). She was complicated by diabetic nephropathy and requiring hemodialysis. She had first noticed pain and swelling in her left thigh after a minimal trauma for 2 days prior to presentation. Clinical and laboratory evaluation, and muscle biopsy revealed the diagnosis of muscle infarctions. She did no respond to the conservative therapy. Pain and swelling in her thigh worsened progressively. She underwent surgical debridment and then, her clinical status improved. We describe the characteristic clinical and pathologic findings and the course of the illness with emphasis on the importance of recognition of the syndrome so that unnecessary investigation and overzealous therapy can be avoided.
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GE Umpierrez RG Stiles J Kleinbart et al. (1996) ArticleTitleDiabetic muscle infarction Am J Med 101 245–250 Occurrence Handle10.1016/S0002-9343(96)00156-8 Occurrence Handle8873484 Occurrence Handle1:STN:280:ByiD38jjsVE%3D
L Silberstein KE Britton FP Marsh et al. (2001) ArticleTitleAn unexpected cause of muscle pain in diabetes Ann Rheum Dis 60 310–312 Occurrence Handle10.1136/ard.60.4.310 Occurrence Handle11247854 Occurrence Handle1:STN:280:DC%2BD3M3gslGqtA%3D%3D
L Angervall B Stener (1965) ArticleTitleTumoriform focal muscle degeneration in two diabetic patients Diabetologia 1 39–42 Occurrence Handle10.1007/BF01338714
CS Chester BQ Banker (1986) ArticleTitleFocal infarction of muscle in diabetics Diabetes Care 9 623–630 Occurrence Handle3803154 Occurrence Handle1:STN:280:BiiC3cvpslM%3D
B Boluda J Mesa G Obiols R. Simo (1989) ArticleTitleFocal muscle infarction in a diabetic Diabetes Metab 15 269–270 Occurrence Handle1:STN:280:By%2BB3c7ltFI%3D
KL Barton BF Palmer (1993) ArticleTitleBilateral infarction of the vastus lateralis muscle in a diabetic patient: a case report and review of the literature J Diabetes Complications 7 221–223 Occurrence Handle8219365 Occurrence Handle1:STN:280:ByuD3szntFc%3D
C Bingham DA Hilton AJ Nicholls (1998) ArticleTitleDiabetic muscle infarction: an unsual cause of leg swelling in a diabetic on continous ambulatory peritoneal dialysis Nephrol Dial Transplant 13 2377–2379 Occurrence Handle9761529 Occurrence Handle1:STN:280:DyaK1cvjt1KqtA%3D%3D
JS Jelinec MD Murphey AJ Aboulafia et al. (1999) Radiology 211 241–247
EK Bjornskov MR Carry FH Katz et al. (1995) ArticleTitleDiabetic muscle infarction: a new perspective on pathogenesis and management Neuromuscul Disord 5 39–45 Occurrence Handle7719140 Occurrence Handle1:STN:280:ByqB3srjt1I%3D
BQ Banker CS Chester (1973) ArticleTitleInfarction of thigh muscle in the diabetic patient Neurology 23 667–677 Occurrence Handle4736486 Occurrence Handle1:STN:280:CSyB3c7ltlM%3D
BN Becker CC Otley DB MacNeill et al. (1992) ArticleTitleMicroangiopathic ischemic myopathy of semimembranosus muscle with diabetes mellitus Diabetes Care15 586–587
PV Rocca JA Alloway DJ Hashel (1993) ArticleTitleDiabetic muscle infarction Semin Arthritis Rheum 22 280–287 Occurrence Handle8484135 Occurrence Handle1:STN:280:ByyB2cflvVA%3D
JL Ratliff J Matthews JC Blalock JV Kasin (1986) ArticleTitleInfarction of the quadriceps muscle: a complication of diabetic vasculopathy South Med J 79 1595b
MR Schmid T Kossmann S Duewell (1998) ArticleTitleDifferentiation of necrotizing fasciitis and cellulitis using MR imaging Ajr Amj Roentgenol 170 615–620 Occurrence Handle1:STN:280:DyaK1c7ltFKnsg%3D%3D
E Moskovic C Fisher G Westbury C Parsons (1991) ArticleTitleFocal myositis, a benign inflammatory pseudotumor: CT appearances Br J Radiol 64 489–493 Occurrence Handle2070176 Occurrence Handle1:STN:280:By6A3c%2Fit1c%3D
RJ Barohn JT Kissel (1992) ArticleTitleCase-of-the-month: painful thigh mass in a young woman—diabetic muscle infarction Muscle Nerve 15 850–852 Occurrence Handle10.1002/mus.880150715 Occurrence Handle1501628 Occurrence Handle1:STN:280:By2A28rntFI%3D
S Reich SN Wiener CS Chester R Ruff (1985) ArticleTitleClinical and radiological features of spontaneous muscle infarction in the diabetic Clin Nucl Med 10 876–879 Occurrence Handle4075687 Occurrence Handle1:STN:280:BimD1c%2FktFQ%3D
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Sahin, I., Taskapan, C., Taskapan, H. et al. Diabetic Muscle Infraction: An Unusual Cause of Muscle Pain in a Diabetic Patient on Hemodialysis. Int Urol Nephrol 37, 629–632 (2005). https://doi.org/10.1007/s11255-005-0394-y
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DOI: https://doi.org/10.1007/s11255-005-0394-y