American Journal of Obstetrics and Gynecology
Maternal postprandial glucose levels and infant birth weight: The Diabetes in Early Pregnancy Study*
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2022, Endocrine PracticeCitation Excerpt :The goals of preconception care should be tight glycemic control with an A1C <6.5%, without significant hypoglycemia, which will lower risks of congenital malformations, preeclampsia, and perinatal mortality.113 The HAPO study showed that increasing glycemia is associated with increased neonatal adverse outcomes such as macrosomia, neonatal hypoglycemia, and cesarean delivery.64,115-119 The targets for glycemic control during pregnancy for women with preexisting DM and GDM are based on the physiology of nondiabetic pregnancies.
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- *
Supported by the National. Institute of Child Health and Human Development—Diabetes in Early Pregnancy Study and Clinical Research Grants RR00037-28 and RR0047.
- a
From the Samum Medical Research Foundation
- b
the National Institute of Child Health and Human Development
- c
Northwestern University
- d
the University of Washington
- e
the University of Pittsburgh.