Clinical InvestigationsOutcomes, Health Policy, and Managed CareHealth-related quality of life and long-term mortality in patients treated with percutaneous coronary intervention
Section snippets
Study population
The initial study population included 875 consecutive patients (response rate = 71%) treated with PCI with either sirolimus-eluting stents (SESs) or bare metal stent implantation between October 16, 2001, and October 15, 2002, as part of the RESEARCH registry who participated in the psychological substudy.9 The design of the RESEARCH registry has been published elsewhere.10 Briefly, the RESEARCH registry is a single-center registry evaluating the safety and efficacy of SES implantation in
Baseline characteristics
Patient baseline characteristics for the total sample at 6-year follow-up are presented in Table I. Mean age in the population was 62 years and 72% were men. There were 96 deaths during the 6-year follow-up period. The average follow-up time was 6.0 years (range 4-7 years).
Nonresponders on the SF-36 at 1 or 12 months were similar divided as compared with responders on most clinical baseline characteristics. Only more previous PCI was present in the nonresponders (32% vs 23%, P = .03).
Poor health status as predictor of 6-year mortality
The
Discussion
In the current study, we found that poor health status, as measured with the SF-36, is a strong, independent predictor of 6-year mortality in PCI patients treated in the drug-eluting stent era, with the associated adjusted HRs ranging from 1.73 to 2.76. In contrast, we did not find any relation between a decline in health status between 1 and 12 months and mortality at 6 years.
Several other studies have shown that poor health status predicts adverse clinical outcome in patients with heart
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Longitudinal associations of self-reported satisfaction with life and vitality with risk of mortality
2021, Journal of Psychosomatic ResearchAssociation between illness perception and health-related quality of life in patients with preexisting premature coronary artery disease
2019, Journal of Psychosomatic ResearchCitation Excerpt :HRQoL is a broad multidimensional concept in which patients' focus is on their subjective experience of the physical, mental, emotional, and social functioning; [10] and it is negatively correlated with worth outcome in patients with CAD. HRQoL decreases in CAD, [11] and previous investigators not only have shown that HRQoL is a predictor of mortality and rehospitalization [12–15] but also have suggested that it is a useful option for improving risk stratification among patients with CAD. [13,16] Differences in illness perception and HRQoL have been observed among patients with CAD in terms of age.
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2018, Mental Health and PreventionAge does matter: Younger pPCI patients profit more from cardiac rehabilitation than older patients
2017, International Journal of CardiologyCitation Excerpt :Although not confirmed by all studies, improvements in SHS possibly remain at follow-up [2]. Improving the subjective health status is an important objective, as a poor subjective health status is associated with a worse prognosis [7,8]. CR programs in older coronary artery disease patients have a positive influence on lipids [9], obesity indexes and exercise capacity [9,10].
The association between subjective health status and 14-year mortality in post-PCI patients
2017, International Journal of CardiologySense of coherence as a mediator between hostility and health-related quality of life among coronary heart disease patients
2016, Heart and Lung: Journal of Acute and Critical CareCitation Excerpt :Along with the increased importance of prevention, health-related quality of life (HRQoL) has gained attention and become an important outcome in patients with CHD.2–4 For example, poor HRQoL has been shown to be independently associated with both onset and progression of CHD.5–7 HRQoL is at present recognised as a clinically relevant construct useful for assessment of the impact of CHD on patient, the effectiveness of interventions and the risk for future CHD.