Medical ProgressThe global spread of type 2 diabetes mellitus in children and adolescents
Section snippets
Methods
The Medline database and Cochrane Library online were searched for articles on T2DM in children and adolescents published between September 1978 and May 2004 in all languages. Searches were performed by using the following key words alone and in combination: non–insulin-dependent diabetes mellitus, type 2 diabetes mellitus, children, adolescents, and youth. A total of 1902 publications were identified; however, only 110 contained epidemiologic data on T2DM in children and adolescents, including
Results
The apparent prevalence and incidence of T2DM determined from population-based studies in specific countries or regions are presented in Figure 1 and Figure 2, respectively. The percentages of new cases of diabetes in children and adolescents reported to have T2DM are presented in Figure 3.
The recent recognition of T2DM in children and the recent proliferation of reports in the literature from around the world is illustrated by the number of publication included in our report: Before 1990,
Discussion
This review confirms the rise over the last two decades in the global recognition and report of T2DM in children and adolescents. Historically, the first cases were reported in 1979 and 1984 among Native Americans and Canadian First Nation People, who were regarded as homogenous groups with a genetic susceptibility to T2DM. The second wave of reports appeared in the mid-1990s and involved predominately ethnic minorities, namely blacks and Hispanic Americans and some white populations in the
References (70)
- et al.
Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective
J Pediatr
(2000) - et al.
Epidemiology of type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in Japanese children
Diabetes Res Clin Pract
(1994) The changing demography of diabetes mellitus in Singapore
Diabetes Res Clin Pract
(2000)- et al.
Clinical features of diabetes in the young as seen at a diabetes center in south India
Diabetes Res Clin Pract
(1988) - et al.
Early presentation of type 2 diabetes mellitus in young New Zealand Maori
Diabetes Res Clin Pract
(1999) - et al.
Childhood and adolescent diabetes mellitus in Arabs residing in the United Arab Emirates
Diabetes Res Clin Pract
(2002) - et al.
Three-year prevalence and incidence of diabetes among American Indian youth in Montana and Wyoming, 1999 to 2001
J Pediatr
(2003) - et al.
Childhood obesity: public-health crisis, common sense cure
Lancet
(2002) - et al.
Adolescent obesity increases significantly in second and third generation US immigrants: the National Longitudinal Study of Adolescent Health
J Nutr
(1998) - et al.
The high prevalence of diabetes mellitus and hyperinsulinemia among the Japanese-Americans living in Hawaii and Los Angeles
Diabetes Res Clin Pract
(1994)