Original ArticleAssociation of Short and Long Sleep Durations with Insulin Sensitivity in Adolescents
Section snippets
Methods
This sample comprised adolescents participating in the Cleveland Children’s Sleep and Health Study (CCSHS), an ongoing longitudinal cohort study designed to evaluate sleep measures and their health outcomes. As previously described,27, 28, 29 the cohort was originally assembled by stratified sampling of full-term and preterm (<37 weeks gestational age) children born between 1988 and 1993 and was designed to over-represent African-American and preterm children. The first CCSHS examination
Results
Sample characteristics for the analytic sample and stratified by mean sleep duration category are shown in Table I. Consistent with the sampling strategy, approximately half the sample was male and had been born preterm, and 42.7% of the sample were minority race (predominantly African-American). Approximately 20% of the sample was obese, and approximately 26% had a G:I ratio <7. Mean weekday sleep duration was 7.63 ± 1.08 hours and was similar for participants in the early adolescent
Discussion
This study evaluated the relationship between an objective measure of habitual sleep duration (with actigraphy) and an index of insulin sensitivity in an adolescent population. In this sample, a birth cohort from an urban Midwestern area assembled to over-represent minorities and preterm children, we observed shorter sleep duration to be associated with minority race and indices of adiposity. As expected, increased HOMA levels were associated with adiposity, decreased physical activity,
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Supported by grants from the National Institutes of Health (NIH HL07567, HL60957, UL1-RR024989, and 1U54CA116867). The authors declare no conflicts of interest.