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Longitudinal association between dairy consumption and changes of body weight and waist circumference: the Framingham Heart Study

International Journal of Obesity volume 38, pages 299–305 (2014)Cite this article

Subjects

Abstract

Background:

Dairy foods are nutrient dense and may be protective against long-term weight gain.

Objective:

We aimed to examine the longitudinal association between dairy consumption and annualized changes in weight and waist circumference (WC) in adults.

Methods:

Members of the Framingham Heart Study Offspring Cohort who participated in the fifth through eighth study examinations (1991–2008) were included in these analyses (3440 participants with 11 683 observations). At each exam, dietary intake was assessed by a validated food frequency questionnaire, and weight and WC were assessed following standardized procedures. Repeated measures models were used for the longitudinal analyses of annualized weight and waist circumference changes, adjusting for time-varying or invariant covariates.

Results:

On average, participants gained weight and WC during follow-up. Dairy intake increased across exams. After adjusting for demographic and lifestyle factors (including diet quality), participants who consumed ⩾3 servings per day of total dairy had 0.10 kg (±0.04) smaller annualized increment of weight (Ptrend=0.04) than those consuming <1 serving per day. Higher total dairy intake was also marginally associated with less WC gain (Ptrend=0.05). Similarly, participants who consumed ⩾3 servings per week of yogurt had a 0.10 kg (±0.04) and 0.13 cm (±0.05) smaller annualized increment of weight (Ptrend=0.03) and WC (Ptrend=0.008) than those consuming <1 serving per week, respectively. Skim/low-fat milk, cheese, total high-fat or total low-fat dairy intake were not associated with long-term change in weight or WC.

Conclusion:

Further longitudinal and interventional studies are warranted to confirm the beneficial role of increasing total dairy and yogurt intake, as part of a healthy and calorie-balanced dietary pattern, in the long-term prevention of gain in weight and WC.

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References

  1. World Health Organization. Controlling the Global Obesity Epidemic. www.who.int/nutrition/topics/obesity/en/. Accessed 2012.

  2. Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL . Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord 1998; 22: 39–47.

    Article  CAS  PubMed  Google Scholar 

  3. Ogden CL, Carroll MD, Kit BK, Flegal KM . Prevalence of obesity in the United States, 2009–2010. NCHS data brief, no 82. NCHS data brief, no 82 2012. National Center for Health Statistics: Hyattsville, MD, 2012.

  4. Mathieu P, Lemieux I, Despres JP . Obesity, inflammation, and cardiovascular risk. Clin Pharmacol Ther 2010; 87: 407–416.

    Article  CAS  PubMed  Google Scholar 

  5. Despres JP, Arsenault BJ, Cote M, Cartier A, Lemieux I . Abdominal obesity: the cholesterol of the 21st century? Can J Cardiol 2008; 24 (Suppl D): 7D–12D.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Finkelstein EA, Trogdon JG, Cohen JW, Dietz W . Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff (Millwood) 2009; 28: w822–w831.

    Article  Google Scholar 

  7. United States Department of Agriculture. Dietary Guidelines for Americans, 2010 (Policy Document). Released 1/31/11; 2012.

  8. Louie JC, Flood VM, Hector DJ, Rangan AM, Gill TP . Dairy consumption and overweight and obesity: a systematic review of prospective cohort studies. Obes Rev 2011; 12: e582–e592.

    Article  CAS  PubMed  Google Scholar 

  9. Dougkas A, Reynolds CK, Givens ID, Elwood PC, Minihane AM . Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms. Nutr Res Rev 2011; 24: 72–95.

    Article  PubMed  Google Scholar 

  10. Chen M, Pan A, Malik VS, Hu FB . Effects of dairy intake on body weight and fat: a meta-analysis of randomized controlled trials. Am J Clin Nutr 2012; 96: 735–747.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Abargouei AS, Janghorbani M, Salehi-Marzijarani M, Esmaillzadeh A . Effect of dairy consumption on weight and body composition in adults: a systematic review and meta-analysis of randomized controlled clinical trials. Int J Obes (Lond) 2012; 36: 1485–1493.

    Article  CAS  Google Scholar 

  12. Wu T, Gao X, Chen M, van Dam RM . Long-term effectiveness of diet-plus-exercise interventions vs. diet-only interventions for weight loss: a meta-analysis. Obes Rev 2009; 10: 313–323.

    Article  CAS  PubMed  Google Scholar 

  13. Curioni CC, Lourenco PM . Long-term weight loss after diet and exercise: a systematic review. Int J Obes (Lond) 2005; 29: 1168–1174.

    Article  CAS  Google Scholar 

  14. Rosell M, Hakansson NN, Wolk A . Association between dairy food consumption and weight change over 9 y in 19,352 perimenopausal women. Am J Clin Nutr 2006; 84: 1481–1488.

    Article  CAS  PubMed  Google Scholar 

  15. Meydani SN, Ha WK . Immunologic effects of yogurt. Am J Clin Nutr 2000; 71: 861–872.

    Article  CAS  PubMed  Google Scholar 

  16. Adolfsson O, Meydani SN, Russell RM . Yogurt and gut function. Am J Clin Nutr 2004; 80: 245–256.

    Article  CAS  PubMed  Google Scholar 

  17. Wang H, Livingston KA, Fox CS, Meigs JB, Jacques PF . Yogurt consumption is associated with better diet quality and metabolic profile in American men and women. . Nutr Res 2013; 33: 18–26.

    Article  PubMed  Google Scholar 

  18. Usinger L, Ibsen H, Jensen LT . Does fermented milk possess antihypertensive effect in humans? J Hypertens 2009; 27: 1115–1120.

    Article  CAS  PubMed  Google Scholar 

  19. Framingham Heart Study. www.framinghamheartstudy.org. Accessed 2012.

  20. Rimm EB, Giovannucci EL, Stampfer MJ, Colditz GA, Litin LB, Willett WC . Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. Am J Epidemiol 1992; 135: 1114–1126 discussion 1127-36.

    Article  CAS  PubMed  Google Scholar 

  21. Willett WC, Reynolds RD, Cottrell-Hoehner S, Sampson L, Browne ML . Validation of a semi-quantitative food frequency questionnaire: comparison with a 1-year diet record. J Am Diet Assoc 1987; 87: 43–47.

    CAS  PubMed  Google Scholar 

  22. Salvini S, Hunter DJ, Sampson L, Stampfer MJ, Colditz GA, Rosner B et al. Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol 1989; 18: 858–867.

    Article  CAS  PubMed  Google Scholar 

  23. Willett WC . Food frequency methods. Nutritional Epidemiology.. Oxford University Press: New York pp 74–91 1998.

  24. US Department of Agriculture. National Nutrient Database for Standard Reference, Release 25. www.ars.usda.gov/SP2UserFiles/Place/12354500/Data/SR25/sr25_doc.pdf. Accessed 2012.

  25. Fogli-Cawley JJ, Dwyer JT, Saltzman E, McCullough ML, Troy LM, Jacques PF . The 2005 Dietary Guidelines for Americans Adherence Index: development and application. J Nutr 2006; 136: 2908–2915.

    Article  CAS  PubMed  Google Scholar 

  26. Kannel WB, Sorlie P . Some health benefits of physical activity. The Framingham Study. Arch Intern Med 1979; 139: 857–861.

    Article  CAS  PubMed  Google Scholar 

  27. World Health Organization. WHO Expert Committee on Diabetes Mellitus: Second Report. 1980.

  28. McNamara JR, Schaefer EJ . Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions. Clin Chim Acta 1987; 166: 1–8.

    Article  CAS  PubMed  Google Scholar 

  29. Warnick GR, Benderson J, Albers JJ . Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 1982; 28: 1379–1388.

    CAS  PubMed  Google Scholar 

  30. Preis SR, Massaro JM, Robins SJ, Hoffmann U, Vasan RS, Irlbeck T et al. Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study. Obesity (Silver Spring) 2010; 18: 2191–2198.

    Article  Google Scholar 

  31. Chau D, Cho LM, Jani P St, Jeor ST . Individualizing recommendations for weight management in the elderly. Curr Opin Clin Nutr Metab Care 2008; 11: 27–31.

    Article  PubMed  Google Scholar 

  32. Han TS, Tajar A, Lean ME . Obesity and weight management in the elderly. Br Med Bull 2011; 97: 169–196.

    Article  CAS  PubMed  Google Scholar 

  33. Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med 2006; 355: 763–778.

    Article  CAS  PubMed  Google Scholar 

  34. Huang Z, Willett WC, Manson JE, Rosner B, Stampfer MJ, Speizer FE et al. Body weight, weight change, and risk for hypertension in women. Ann Intern Med 1998; 128: 81–88.

    Article  CAS  PubMed  Google Scholar 

  35. Panico S, Palmieri L, Donfrancesco C, Vanuzzo D, Chiodini P, Cesana G et al. Preventive potential of body mass reduction to lower cardiovascular risk: the Italian Progetto CUORE study. Prev Med 2008; 47: 53–60.

    Article  PubMed  Google Scholar 

  36. Lanou AJ, Barnard ND . Dairy and weight loss hypothesis: an evaluation of the clinical trials. Nutr Rev 2008; 66: 272–279.

    Article  PubMed  Google Scholar 

  37. Pereira MA, Jacobs DR Jr, Van Horn L, Slattery ML, Kartashov AI, Ludwig DS . Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA 2002; 287: 2081–2089.

    Article  PubMed  Google Scholar 

  38. Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB . Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med 2011; 364: 2392–2404.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Vergnaud AC, Peneau S, Chat-Yung S, Kesse E, Czernichow S, Galan P et al. Dairy consumption and 6-y changes in body weight and waist circumference in middle-aged French adults. Am J Clin Nutr 2008; 88: 1248–1255.

    CAS  PubMed  Google Scholar 

  40. Drapeau V, Despres JP, Bouchard C, Allard L, Fournier G, Leblanc C et al. Modifications in food-group consumption are related to long-term body-weight changes. Am J Clin Nutr 2004; 80: 29–37.

    Article  CAS  PubMed  Google Scholar 

  41. Zemel MB . The role of dairy foods in weight management. J Am Coll Nutr 2005; 24: 537S–546SS.

    Article  CAS  PubMed  Google Scholar 

  42. Zemel MB, Thompson W, Milstead A, Morris K, Campbell P . Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 2004; 12: 582–590.

    Article  CAS  PubMed  Google Scholar 

  43. Zemel MB, Richards J, Milstead A, Campbell P . Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res 2005; 13: 1218–1225.

    Article  CAS  PubMed  Google Scholar 

  44. Pfeuffer M, Schrezenmeir J . Milk and the metabolic syndrome. Obes Rev 2007; 8: 109–118.

    Article  CAS  PubMed  Google Scholar 

  45. Diamant M, Blaak EE, de Vos WM . Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes? Obes Rev 2011; 12: 272–281.

    Article  CAS  PubMed  Google Scholar 

  46. Arora T, Sharma R . Fermentation potential of the gut microbiome: implications for energy homeostasis and weight management. Nutr Rev 2011; 69: 99–106.

    Article  PubMed  Google Scholar 

  47. Rajpathak SN, Rimm EB, Rosner B, Willett WC, Hu FB . Calcium and dairy intakes in relation to long-term weight gain in US men. Am J Clin Nutr 2006; 83: 559–566.

    Article  CAS  PubMed  Google Scholar 

  48. Sanchez-Villegas A, Bes-Rastrollo M, Martinez-Gonzalez MA, Serra-Majem L . Adherence to a Mediterranean dietary pattern and weight gain in a follow-up study: the SUN cohort. Int J Obes (Lond) 2006; 30: 350–358.

    Article  CAS  Google Scholar 

  49. Terpstra AH . Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. Am J Clin Nutr 2004; 79: 352–361.

    Article  CAS  PubMed  Google Scholar 

  50. Larsen TM, Toubro S, Astrup A . Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies. J Lipid Res 2003; 44: 2234–2241.

    Article  CAS  PubMed  Google Scholar 

  51. Smedman AE, Gustafsson IB, Berglund LG, Vessby BO . Pentadecanoic acid in serum as a marker for intake of milk fat: relations between intake of milk fat and metabolic risk factors. Am J Clin Nutr 1999; 69: 22–29.

    Article  CAS  PubMed  Google Scholar 

  52. Wang H, Steffen LM, Vessby B, Basu S, Steinberger J, Moran A et al. Obesity modifies the relations between serum markers of dairy fats and inflammation and oxidative stress among adolescents. Obesity (Silver Spring) 2011; 19: 2404–2410.

    Article  CAS  Google Scholar 

  53. Beydoun MA, Gary TL, Caballero BH, Lawrence RS, Cheskin LJ, Wang Y . Ethnic differences in dairy and related nutrient consumption among US adults and their association with obesity, central obesity, and the metabolic syndrome. Am J Clin Nutr 2008; 87: 1914–1925.

    Article  CAS  PubMed  Google Scholar 

  54. Hjartaker A, Lagiou A, Slimani N, Lund E, Chirlaque MD, Vasilopoulou E et al. Consumption of dairy products in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort: data from 35 955 24-hour dietary recalls in 10 European countries. Public Health Nutr 2002; 5: 1259–1271.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

We thank Kara A Livingston, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, for the help with data set management. This work was supported by the National Heart, Lung and Blood Institute of the National Institute of Health (contract number: NO1-HC-25195), US Department of Agriculture Agreement 58–1950–7-707 and research grants from The Dannon Company, Inc., and General Mills Bell Institute of Health and Nutrition.

Author contributions

PFJ and NMM designed the research; PFJ and HW conducted the research; JBM, CSF and GTR provided essential materials; HW and GTR analyzed data or performed statistical analysis; HW and PFJ wrote the paper; PFJ had primary responsibility for final content; and LMT, NMM and CSF did critical review.

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Authors and Affiliations

  1. Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA

    H Wang, L M Troy, G T Rogers, N M McKeown & P F Jacques

  2. Department of Nutrition, Chenoweth Laboratory, University of Massachusetts, Amherst, MA, USA

    L M Troy

  3. Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA

    L M Troy, N M McKeown & P F Jacques

  4. National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, MA, USA

    C S Fox

  5. Department of Medicine, Massachusetts General Hospital, General Internal Medicine Unit, Boston, MA, USA

    J B Meigs

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Correspondence to P F Jacques.

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Competing interests

PF Jacques and H Wang received support from a grant from The Dannon Company Inc., PF Jacques is a member of the Dannon Yogurt Advisory Board, NM McKeown and LM Troy were funded in part by a grant from General Mills Bell Institute of Health and Nutrition. G Rogers, C Fox and J Meigs declare no conflict of interest.

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Wang, H., Troy, L., Rogers, G. et al. Longitudinal association between dairy consumption and changes of body weight and waist circumference: the Framingham Heart Study. Int J Obes 38, 299–305 (2014). https://doi.org/10.1038/ijo.2013.78

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