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Bone

Adiposity and bone accrual—still an established paradigm?

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The paradigm that obesity at any age is protective against skeletal failure has been ingrained in clinical practice for several decades. A new study published in the Journal of Bone and Mineral Research challenges the basic framework of that tenet.

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Figure 1: Regulation of bone by adipose tissue.

References

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Correspondence to Clifford J. Rosen.

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Kawai, M., Rosen, C. Adiposity and bone accrual—still an established paradigm?. Nat Rev Endocrinol 6, 63–64 (2010). https://doi.org/10.1038/nrendo.2009.249

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