The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Epidemiological Study of Diabetes Mellitus in the Hiroshima Area-Prevalence of Diabetes Mellitus and Follow-Up Studies Using the Glucose Tolerance Test 5-19 Years after Initial Testing
CHIKAKO ITO
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1983 Volume 141 Issue Suppl Pages 115-118

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Abstract

Tests for diabetes mellitus have been performed annually since 1963 on about 100, 000 A-bomb survivors living in Hiroshima. We report here on the trends over the 19 years leading up to 1981 for the glycosuria positive rate, the 75g GTT results of positive cases and the findings of the 5-19 year follow-up. 1) The glycosuria positive rate was 3-4 times higher in males. During the period of 1963-1979, the positive rate increased annually in both sexes, reaching 2.6 and 3.0 times the male-female values for 1963, but subsequently levelling off. 2) When Body Mass Index (BMI)<25, 24.9% of the sample was diabetic (including those under treatment), 26.0% had Impaired Glucose Tolerance (IGT) and 49.1% were normal, whereas when BMI≥25, the rates were significantly higher being 45.0%, 27.4% and 27.6% respectively (p<0.001). Frequency increased with BMI, reaching 75.0% at BMI 33.3) Results of the 5-19 year follow-up showed the annual diabetes onset rate by the person year method in those with BMI<25 at initial GTT to be 1.72% among 848 normals, while it was a significantly higher 4.82% in those suffering from IGT. For those with BMI≥25, the rates were 3.77% among 161 normals and 7.93% among 132 IGT cases.

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