Objective: To investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).
Method: The plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.
Result: The hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).
Conclusion: Increased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.