Complications of type 1 diabetes

Endocrinol Metab Clin North Am. 2010 Sep;39(3):625-40. doi: 10.1016/j.ecl.2010.05.009.

Abstract

The prevalence of diabetes is increasing worldwide and the concern regarding the number of new cases of diabetes relates to the development of chronic complications. It has been recognized for years that the complications are a cause of considerable morbidity and mortality worldwide and as such, negatively affect the quality of life in individuals with diabetes with an increase in disability and death. Specifically, the complications of diabetes have been classified as either microvascular (ie, retinopathy, nephropathy, and neuropathy) or macrovascular (ie, cardiovascular disease, cerebrovascular accidents, and peripheral vascular disease). For purposes of this article, the authors focus on a brief review of the major complications.

Publication types

  • Review

MeSH terms

  • Animals
  • Blood Pressure / physiology
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / metabolism
  • Diabetes Mellitus, Type 1 / physiopathology
  • Diabetes Mellitus, Type 1 / therapy
  • Diabetic Angiopathies / diagnosis
  • Diabetic Angiopathies / etiology
  • Diabetic Angiopathies / therapy
  • Diabetic Nephropathies / diagnosis
  • Diabetic Nephropathies / etiology
  • Diabetic Nephropathies / physiopathology
  • Diabetic Nephropathies / therapy
  • Diabetic Neuropathies / diagnosis
  • Diabetic Neuropathies / etiology
  • Diabetic Neuropathies / therapy
  • Humans
  • Models, Biological