Prevalence and associated factors of diabetic retinopathy in rural Korea: the Chungju metabolic disease cohort study

J Korean Med Sci. 2011 Aug;26(8):1068-73. doi: 10.3346/jkms.2011.26.8.1068. Epub 2011 Jul 30.

Abstract

This study was aimed to investigate the prevalence of diabetic retinopathy and its associated factors in rural Korean patients with type 2 diabetes. A population-based, cross-sectional diabetic retinopathy survey was conducted from 2005 to 2006 in 1,298 eligible participants aged over 40 yr with type 2 diabetes identified in a rural area of Chungju, Korea. Diabetic retinopathy was diagnosed by a practicing ophthalmologist using funduscopy. The overall prevalence of diabetic retinopathy in the population was 18% and proliferative or severe non-proliferative form was found in 5.0% of the study subjects. The prevalence of retinopathy was 6.2% among those with newly diagnosed type 2 diabetes and 2.4% of them had a proliferative or severe non-proliferative diabetic retinopathy. The odds ratio of diabetic retinopathy increased with the duration of diabetes mellitus (5-10 yr: 5.2- fold; > 10 yr: 10-fold), postprandial glucose levels (> 180 mg/dL: 2.5-fold), and HbA1c levels (every 1% elevation: 1.34-fold). The overall prevalence of diabetic retinopathy in rural Korean patients was similar to or less than that of other Asian group studies. However, the number of patients with proliferative or severe non-proliferative diabetic retinopathy was still high and identified more frequently at the time of diagnosis. This emphasizes that regular screening for diabetic retinopathy and more aggressive management of glycemia can reduce the number of people who develop diabetic retinopathy.

Keywords: Diabetic Retinopathy; Prevalence; Risk Factors.

MeSH terms

  • Aged
  • Blood Glucose / analysis
  • Cohort Studies
  • Diabetes Mellitus, Type 2 / complications
  • Diabetic Retinopathy / complications
  • Diabetic Retinopathy / epidemiology*
  • Diabetic Retinopathy / ethnology
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Prevalence
  • Republic of Korea / epidemiology
  • Risk Factors
  • Rural Population

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human