Are current diagnostic guidelines delaying early detection of dysglycemic states? Time for new approaches

Endocrine. 2013 Aug;44(1):66-9. doi: 10.1007/s12020-013-9873-6. Epub 2013 Jan 17.

Abstract

Diagnosis of dysglycemic states is likely delayed as current diagnostic criteria apply absolute threshold values to a process that is continuous. The importance of this relates to forestalling opportunities for earlier diagnosis when prevention and reversibility are more likely to occur by preventing further β cell dysfunction. Although the optimal method for earlier identification of individuals at risk remains uncertain, the paper suggests novel approaches.

MeSH terms

  • Delayed Diagnosis
  • Diabetes Mellitus / diagnosis
  • Diagnostic Techniques, Endocrine* / adverse effects
  • Diagnostic Techniques, Endocrine* / standards
  • Diagnostic Techniques, Endocrine* / trends
  • Early Diagnosis
  • Glucose / pharmacology
  • Glucose Metabolism Disorders / diagnosis*
  • Humans
  • Insulin-Secreting Cells / drug effects
  • Insulin-Secreting Cells / physiology
  • Practice Guidelines as Topic* / standards
  • Prediabetic State / diagnosis
  • Reference Values

Substances

  • Glucose