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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
2001 2
2002 2
2004 1
2005 1
2006 5
2007 4
2008 2
2009 1
2010 9
2011 3
2012 1
2013 4
2014 10
2015 15
2016 10
2017 14
2018 10
2019 15
2020 21
2021 28
2022 22
2023 22
2024 13

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187 results

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Page 1
Senolytic drugs: from discovery to translation.
Kirkland JL, Tchkonia T. Kirkland JL, et al. Among authors: tchkonia t. J Intern Med. 2020 Nov;288(5):518-536. doi: 10.1111/joim.13141. Epub 2020 Aug 4. J Intern Med. 2020. PMID: 32686219 Free PMC article. Review.
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
Saul D, Kosinsky RL, Atkinson EJ, Doolittle ML, Zhang X, LeBrasseur NK, Pignolo RJ, Robbins PD, Niedernhofer LJ, Ikeno Y, Jurk D, Passos JF, Hickson LJ, Xue A, Monroe DG, Tchkonia T, Kirkland JL, Farr JN, Khosla S. Saul D, et al. Among authors: tchkonia t. Nat Commun. 2022 Aug 16;13(1):4827. doi: 10.1038/s41467-022-32552-1. Nat Commun. 2022. PMID: 35974106 Free PMC article.
Cellular senescence and senolytics: the path to the clinic.
Chaib S, Tchkonia T, Kirkland JL. Chaib S, et al. Among authors: tchkonia t. Nat Med. 2022 Aug;28(8):1556-1568. doi: 10.1038/s41591-022-01923-y. Epub 2022 Aug 11. Nat Med. 2022. PMID: 35953721 Free PMC article. Review.
COVID-19 and cellular senescence.
Schmitt CA, Tchkonia T, Niedernhofer LJ, Robbins PD, Kirkland JL, Lee S. Schmitt CA, et al. Among authors: tchkonia t. Nat Rev Immunol. 2023 Apr;23(4):251-263. doi: 10.1038/s41577-022-00785-2. Epub 2022 Oct 5. Nat Rev Immunol. 2023. PMID: 36198912 Free PMC article. Review.
Cellular Senescence: A Translational Perspective.
Kirkland JL, Tchkonia T. Kirkland JL, et al. Among authors: tchkonia t. EBioMedicine. 2017 Jul;21:21-28. doi: 10.1016/j.ebiom.2017.04.013. Epub 2017 Apr 12. EBioMedicine. 2017. PMID: 28416161 Free PMC article. Review.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: tchkonia t. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Cellular senescence mediates fibrotic pulmonary disease.
Schafer MJ, White TA, Iijima K, Haak AJ, Ligresti G, Atkinson EJ, Oberg AL, Birch J, Salmonowicz H, Zhu Y, Mazula DL, Brooks RW, Fuhrmann-Stroissnigg H, Pirtskhalava T, Prakash YS, Tchkonia T, Robbins PD, Aubry MC, Passos JF, Kirkland JL, Tschumperlin DJ, Kita H, LeBrasseur NK. Schafer MJ, et al. Among authors: tchkonia t. Nat Commun. 2017 Feb 23;8:14532. doi: 10.1038/ncomms14532. Nat Commun. 2017. PMID: 28230051 Free PMC article.
Fisetin is a senotherapeutic that extends health and lifespan.
Yousefzadeh MJ, Zhu Y, McGowan SJ, Angelini L, Fuhrmann-Stroissnigg H, Xu M, Ling YY, Melos KI, Pirtskhalava T, Inman CL, McGuckian C, Wade EA, Kato JI, Grassi D, Wentworth M, Burd CE, Arriaga EA, Ladiges WL, Tchkonia T, Kirkland JL, Robbins PD, Niedernhofer LJ. Yousefzadeh MJ, et al. Among authors: tchkonia t. EBioMedicine. 2018 Oct;36:18-28. doi: 10.1016/j.ebiom.2018.09.015. Epub 2018 Sep 29. EBioMedicine. 2018. PMID: 30279143 Free PMC article.
187 results