Understanding the mechanisms by which specific genes are expressed in a temporal or
tissue-specific manner is a central problem in biology. Transcription factors play a key role in …

Heart failure is one of the leading causes of hospitalizations in the United States.
Concomitant and significant renal dysfunction is common in patients with heart failure …

This review of material relevant to the Conference on Biosignature Preservation and
Detection in Mars Analog Environments summarizes the meeting materials and discussions …

We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease
(AD) involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 …

CBP (CREB-binding protein) and p300 are versatile coactivators that link transcriptional
activators to the basal transcriptional apparatus. In the present study, we identify CBP and …

The common interpretation of the positive correlation among self-efficacy, personal goals,
and performance is questioned. Using self-efficacy theory (A. Bandura, 1977), it was …

In the present manuscript we draw on the Multi-Threat Framework to explore gender-related
math attitudes and how they put girls and women at risk for stereotype threats. Gunderson et …

A number of pathophysiologically relevant genes, including platelet-derived growth factor B-
chain (PDGF-B), are induced in the vasculature after acute mechanical injury. In rat aorta …

Transcriptional activation of the IFNβ gene in response to virus infection requires the
assembly of an enhanceosome, consisting of the transcriptional activators NF-κB, IRF1 …

Performing genetic studies in multiple human populations can identify disease risk alleles
that are common in one population but rare in others, with the potential to illuminate …