[HTML][HTML] Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …
that seeks to reduce errors and optimize outcomes when making medical decisions and …
Adiposity, dysmetabolic traits, and earlier onset of female puberty in adolescent offspring of women with gestational diabetes mellitus: a clinical study within the Danish …
OBJECTIVE Offspring of pregnancies affected by gestational diabetes mellitus (GDM) are at
increased risk of the development of type 2 diabetes. However, the extent to which these …
increased risk of the development of type 2 diabetes. However, the extent to which these …
[HTML][HTML] Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations
Aims/hypothesis Gestational diabetes mellitus (GDM) is a common complication of
pregnancy that has substantial short-and long-term adverse health implications for women …
pregnancy that has substantial short-and long-term adverse health implications for women …
Increased expression of microRNA-15a and microRNA-15b in skeletal muscle from adult offspring of women with diabetes in pregnancy
A Houshmand-Oeregaard, M Schrölkamp… - Human molecular …, 2018 - academic.oup.com
Offspring of women with diabetes in pregnancy exhibit skeletal muscle insulin resistance
and are at increased risk of developing type 2 diabetes, potentially mediated by epigenetic …
and are at increased risk of developing type 2 diabetes, potentially mediated by epigenetic …
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations
M Li, ML Rahman, J Wu, M Ding, JE Chavarro… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Objective Women with a history of gestational diabetes mellitus (GDM) have an
exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic …
exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic …
Increased leptin, decreased adiponectin and FGF21 concentrations in adolescent offspring of women with gestational diabetes
FB Kampmann, ACB Thuesen, L Hjort… - European journal of …, 2019 - academic.oup.com
Objective Fetal exposure to gestational diabetes mellitus (GDM) increases the risk of
metabolic diseases in the offspring. Leptin, adiponectin, and fibroblast growth factor 21 …
metabolic diseases in the offspring. Leptin, adiponectin, and fibroblast growth factor 21 …
[HTML][HTML] 14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes
AP Gjesing, L Engelbrechtsen, ACB Thuesen… - Diabetes Research and …, 2022 - Elsevier
Aims Rare variants in the glucokinase gene (GCK) cause Maturity-Onset Diabetes of the
Young (MODY2/GCK-MODY). We investigated the prevalence of GCK variants, phenotypic …
Young (MODY2/GCK-MODY). We investigated the prevalence of GCK variants, phenotypic …
[HTML][HTML] Circulating Metabolomic and Lipidomic Signatures Identify a Type 2 Diabetes Risk Profile in Low-Birth-Weight Men with Non-Alcoholic Fatty Liver Disease
LO Elingaard-Larsen, SO Villumsen, L Justesen… - Nutrients, 2023 - mdpi.com
The extent to which increased liver fat content influences differences in circulating
metabolites and/or lipids between low-birth-weight (LBW) individuals, at increased risk of …
metabolites and/or lipids between low-birth-weight (LBW) individuals, at increased risk of …
[HTML][HTML] Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition
Aims/hypothesis Low birthweight is a risk factor for type 2 diabetes. Most previous studies
are based on cross-sectional prevalence data, not designed to study the timing of onset of …
are based on cross-sectional prevalence data, not designed to study the timing of onset of …
Prospective study of gestational diabetes and fatty liver scores 9 to 16 years after pregnancy
Background Women with gestational diabetes mellitus (GDM) may be at an increased risk of
liver complications because chronic hyperglycemia is a risk factor for liver fat accumulation …
liver complications because chronic hyperglycemia is a risk factor for liver fat accumulation …