Background: The risks and benefits of coxibs, non-steroidal anti-inflammatory drugs
(NSAIDs), and aspirin treatment are under intense debate. Objective: To determine the risk …

OBJECTIVES After the withdrawal of some cyclooxygenase-2 (COX-2) selective inhibitors,
traditional nonsteroidal anti-inflammatory drug (NSAID) use has increased, but without …

BACKGROUND: There are currently limited data regarding the epidemiology of anaphylaxis.
OBJECTIVE: To estimate the incidence of anaphylaxis from all causes, to explore the variety …

Background: The aetiology of inflammatory bowel disease remains largely unknown. Aim:
We performed a comprehensive assessment of potential risk factors associated with the …

Background—Nonsteroidal antiinflammatory drugs (NSAIDs) are reversible inhibitors of
cyclooxygenase (COX)-1 and COX-2. Whether transient and incomplete COX-1 inhibition …

Objective: To investigate the relationship between hemorrhagic stroke and use of
antiplatelets and warfarin using data from The Health Improvement Network. Methods: A …

Background Observational studies have consistently shown that aspirin and non-steroidal
anti-inflammatory drug (NSAID) use is associated with a close to 50% reduced risk of …

Objective: To investigate short-term case fatality and long-term mortality after intracerebral
hemorrhage (ICH) and subarachnoid hemorrhage (SAH) using data from The Health …

Non‐steroidal anti‐inflammatory drugs (NSAIDs) have been associated with upper
gastrointestinal complications such as bleeding or perforation. Paracetamol has been …

Deciphering the genetic landscape of Alzheimer's disease (AD) is essential to define the
pathophysiological pathways involved and to successfully translate genomics to potential …