[HTML][HTML] Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity

D Val-Laillet, E Aarts, B Weber, M Ferrari… - NeuroImage: Clinical, 2015 - Elsevier
Functional, molecular and genetic neuroimaging has highlighted the existence of brain
anomalies and neural vulnerability factors related to obesity and eating disorders such as …

Vagus nerve stimulation: state of the art of stimulation and recording strategies to address autonomic function neuromodulation

D Guiraud, D Andreu, S Bonnet… - Journal of neural …, 2016 - iopscience.iop.org
Objective. Neural signals along the vagus nerve (VN) drive many somatic and autonomic
functions. The clinical interest of VN stimulation (VNS) is thus potentially huge and has …

[HTML][HTML] Dietary sugars: their detection by the gut–brain axis and their peripheral and central effects in health and diseases

M Ochoa, JP Lalles, CH Malbert… - European journal of …, 2015 - Springer
Background Substantial increases in dietary sugar intake together with the increasing
prevalence of obesity worldwide, as well as the parallels found between sugar …

Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study

F Le Jeune, D Drapier, A Bourguignon, J Péron… - Neurology, 2009 - AAN Enterprises
Objective: Apathy may be induced by subthalamic nucleus deep brain stimulation (STN-
DBS) in Parkinson disease (PD). We therefore wished to test the hypothesis that apathy …

Ileal short-chain fatty acids inhibit gastric motility by a humoral pathway

G Cuche, JC Cuber, CH Malbert - American Journal of …, 2000 - journals.physiology.org
The aim of this study was to evaluate the nervous and humoral pathways involved in short-
chain fatty acid (SCFA)-induced ileal brake in conscious pigs. The role of extrinsic ileal …

A three-dimensional digital segmented and deformable brain atlas of the domestic pig

S Saikali, P Meurice, P Sauleau, PA Eliat… - Journal of neuroscience …, 2010 - Elsevier
We used high-magnetic field (4.7 T) magnetic resonance imaging (MRI) to build the first high-
resolution (100μm× 150μm× 100μm) three-dimensional (3D) digital atlas in stereotaxic …

Chronic vagus nerve stimulation decreased weight gain, food consumption and sweet craving in adult obese minipigs

D Val-Laillet, A Biraben, G Randuineau, CH Malbert - Appetite, 2010 - Elsevier
Chronic vagus nerve stimulation (VNS) is known to influence food intake and body weight in
animals and humans. The aim of our work was to evaluate the effects of long-term VNS in …

Changes in brain activity after a diet‐induced obesity

D Val‐Laillet, S Layec, S Guérin, P Meurice… - …, 2011 - Wiley Online Library
Compared to lean subjects, obese men have less activation in the dorsolateral prefrontal
cortex, a brain area implicated in the inhibition of inappropriate behavior, satiety, and meal …

Oral sodium butyrate impacts brain metabolism and hippocampal neurogenesis, with limited effects on gut anatomy and function in pigs

D Val-Laillet, S Guerin, N Coquery, I Nogret… - FASEB …, 2018 - univ-rennes.hal.science
Butyrate can improve gut functions, whereas histone deacetylase inhibitors might alleviate
neurocognitive alterations. Our aim was to assess whether oral butyrate could modulate …

Obesity-associated alterations in glucose metabolism are reversed by chronic bilateral stimulation of the abdominal vagus nerve

CH Malbert, C Picq, JL Divoux, C Henry, M Horowitz - Diabetes, 2017 - Am Diabetes Assoc
Acute vagal stimulation modifies glucose and insulin metabolism, but the effect of chronic
bilateral vagal stimulation is not known. Our aim was to quantify the changes in whole-body …