User profiles for "author:Christos T Nakas"

Christos T Nakas

Professor (Biometry), University of Thessaly, Volos GR && PI, UKC, Inselspital Bern, CH
Verified email at uth.gr
Cited by 3606

Ordered multiple‐class ROC analysis with continuous measurements

CT Nakas, CT Yiannoutsos - Statistics in medicine, 2004 - Wiley Online Library
Receiver operating characteristic (ROC) curves have been useful in two‐group classification
problems. In three‐and multiple‐class diagnostic problems, an ROC surface or hyper …

Developments in ROC surface analysis and assessment of diagnostic markers in three-class classification problems

CT Nakas - REVSTAT-Statistical Journal, 2014 - revstat.ine.pt
This article reviews current state of the art of ROC surface analysis and illustrates its use
through an application on a pancreatic cancer diagnostic marker. Receiver Operating …

Accuracy and cut‐off point selection in three‐class classification problems using a generalization of the Youden index

CT Nakas, TA Alonzo, CT Yiannoutsos - Statistics in medicine, 2010 - Wiley Online Library
We study properties of the index J3, defined as the accuracy, or the maximum correct
classification, for a given three‐class classification problem. Specifically, using J3 one can …

Construction of confidence regions in the ROC space after the estimation of the optimal Youden index-based cut-off point

LE Bantis, CT Nakas, B Reiser - Biometrics, 2014 - academic.oup.com
After establishing the utility of a continuous diagnostic marker investigators will typically
address the question of determining a cut-off point which will be used for diagnostic …

Lipoprotein (a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the …

M Arnold, J Schweizer, CT Nakas, V Schütz… - European heart …, 2021 - academic.oup.com
Abstract Aims Lipoprotein (a)[Lp (a)] is a recognized causal risk factor for atherosclerotic
cardiovascular disease but its role for acute ischaemic stroke (AIS) is controversial. In this …

Resveratrol ameliorates hypoxia/ischemia-induced behavioral deficits and brain injury in the neonatal rat brain

F Karalis, V Soubasi, T Georgiou, CT Nakas… - Brain research, 2011 - Elsevier
Hypoxia–ischemia (HI) induced injury of the neonatal brain accounts for behavioral deficits
concerning mainly neurological reflexes, sensorimotor functions and learning/memory …

[HTML][HTML] The association between nurse staffing and inpatient mortality: A shift-level retrospective longitudinal study

SN Musy, O Endrich, AB Leichtle, P Griffiths… - International journal of …, 2021 - Elsevier
Background Worldwide, hospitals face pressure to reduce costs. Some respond by working
with a reduced number of nurses or less qualified nursing staff. Objective This study aims at …

[HTML][HTML] Computed tomography-based radiomics decodes prognostic and molecular differences in interstitial lung disease related to systemic sclerosis

J Schniering, M Maciukiewicz… - European …, 2022 - Eur Respiratory Soc
Background Radiomic features calculated from routine medical images show great potential
for personalised medicine in cancer. Patients with systemic sclerosis (SSc), a rare …

Perioperative fully closed-loop insulin delivery in patients undergoing elective surgery: an open-label, randomized controlled trial

D Herzig, S Suhner, J Roos, D Schürch… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Perioperative management of glucose levels remains challenging. We aimed to
assess whether fully closed-loop subcutaneous insulin delivery would improve glycemic …

Generalization of Youden index for multiple‐class classification problems applied to the assessment of externally validated cognition in Parkinson disease screening

CT Nakas, JC Dalrymple‐Alford… - Statistics in …, 2013 - Wiley Online Library
Routine cognitive screening in Parkinson disease (PD) has become essential for
management, to track progression and to assess clinical status in therapeutic trials. Patients …