[HTML][HTML] Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs

TH Rim, CJ Lee, YC Tham, N Cheung, M Yu… - The Lancet Digital …, 2021 - thelancet.com
Background Coronary artery calcium (CAC) score is a clinically validated marker of
cardiovascular disease risk. We developed and validated a novel cardiovascular risk …

Retinal photograph-based deep learning predicts biological age, and stratifies morbidity and mortality risk

S Nusinovici, TH Rim, M Yu, G Lee, YC Tham… - Age and …, 2022 - academic.oup.com
Background ageing is an important risk factor for a variety of human pathologies. Biological
age (BA) may better capture ageing-related physiological changes compared with …

Decrease in Choroidal Vascularity Index of Haller's layer in diabetic eyes precedes retinopathy

VHX Foo, P Gupta, QD Nguyen, CCY Chong… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction The study aimed to evaluate Choroidal Vascularity Index (CVI) of Haller's and
Sattler's layers and their relationships with choroidal and retinal thickness, volumes …

Retinal nerve fiber layer thickness and rim area profiles in Asians: pooled analysis from the Asian Eye Epidemiology Consortium

S Majithia, YC Tham, CCY Chong, M Yu, CY Cheung… - Ophthalmology, 2022 - Elsevier
Purpose To evaluate ethnic variations, ocular and systemic determinants of retinal nerve
fiber layer (RNFL) thickness, and neuroretinal rim area among Asians using a large …

[HTML][HTML] Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study

XL Fang, CCY Chong, S Thakur, Z Da Soh, ZL Teo… - Scientific Reports, 2021 - nature.com
We evaluated the 6-year incidence and risk factors of pterygium in a multi-ethnic Asian
population. Participants who attended the baseline visit of the Singapore Epidemiology of …

Normative data and associations of OCT angiography measurements of the macula: the Singapore Malay eye study

ZL Teo, CZ Sun, CCY Chong, YC Tham… - Ophthalmology …, 2022 - Elsevier
Objective To describe the normative quantitative parameters of the macular retinal
vasculature, as well as their systemic and ocular associations using OCT angiography …

Relationship between dry eye symptoms and quality of life: associations and mediation analysis

EWL Lim, CCY Chong, S Nusinovici… - British Journal of …, 2023 - bjo.bmj.com
Purpose (1) To determine the independent association of dry eye symptoms with health-
related quality of life (HRQoL) in the Singapore population and (2) to further investigate …

[HTML][HTML] Associations between Chronic Kidney Disease and Thinning of Neuroretinal Layers in Multiethnic Asian and White Populations

S Majithia, CCY Chong, ML Chee, M Yu, Z Da Soh… - Ophthalmology …, 2024 - Elsevier
Purpose To evaluate the relationships between chronic kidney disease (CKD) with retinal
nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness profiles of …

[HTML][HTML] Circulating metabolites and cardiovascular disease in Asians with chronic kidney disease

J Cai, CCY Chong, CY Cheng, CC Lim… - Cardiorenal …, 2023 - karger.com
Introduction: Chronic kidney disease (CKD) is a growing public health problem, with
significant burden of cardiovascular disease and mortality. The risk of cardiovascular …