Increased sugar consumption is increasingly considered to be a contributor to the worldwide
epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of …

Limited data exist on the performance of high‐throughput proteomics profiling in
epidemiological settings, including the impact of specimen collection and within‐person …

BACKGROUND Soy foods possess both antiestrogenic and estrogen‐like properties. It
remains controversial whether women diagnosed with breast cancer should be advised to …

Experimental studies reported biochemical actions underpinning aging processes and
mortality, but the relevant metabolic alterations in humans are not well understood. Here we …

Background Limited data are available on the prospective relationship between beverage
consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in …

Background Metabolomics profiles were consistently associated with type 2 diabetes (T2D)
risk, but evidence on long-term metabolite changes and T2D incidence is lacking. We …

The consumption of sugar-sweetened beverages (SSB), which includes soft drinks, fruit
drinks, and other energy drinks, is associated with excess energy intake and increased risk …

Aims/hypothesis Sugar-sweetened beverages (SSBs) are a major dietary contributor to
fructose intake. A molecular pathway involving the carbohydrate responsive element …

OBJECTIVE We examined whether intake of methyl donor nutrients, including vitamins B2,
B6, and B12 and folate, from foods and/or supplements is associated with type 2 diabetes …

We assessed longitudinal associations between plasma metabolites, their network-derived
clusters, and type 2 diabetes (T2D) progression in Puerto Rican adults, a high-risk Hispanic …