Adverse effects of glucocorticoids have been abundantly reported. Published reports on low
dose glucocorticoid treatment show that few of the commonly held beliefs about their …

The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional.
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …

Several cardiovascular risk factors (dyslipidaemia, hypertension, glucose intolerance,
hypercoagulability, obesity, hyperinsulinaemia and low-grade inflammation) cluster in the …

Type 1 diabetes is associated with reduced vascular repair, as indicated by impaired wound
healing and reduced collateral formation in ischemia. Recently, endothelial progenitor cells …

To understand organ function, it is important to have an inventory of its cell types and of their
corresponding marker genes. This is a particularly challenging task for human tissues like …

Lgr5 marks adult stem cells in multiple adult organs and is a receptor for the Wnt‐agonistic R‐
spondins (RSPOs). Intestinal, stomach and liver Lgr5+ stem cells grow in 3D cultures to form …

Adult mitotic tissues like the intestine, skin, and blood undergo constant turnover throughout
the life of an organism. Knowing the identity of the stem cell is crucial to understanding …

Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …

Background Innate immunity contributes to the pathogenesis of autoimmune diseases, such
as type 1 diabetes, but until now no randomised, controlled trials of blockade of the key …

Aims The ability to assess endothelial function non-invasively with B-mode ultrasound has
lead to its widespread application in a variety of studies. However, the absolute values …