Background Accumulation of middle-weight uraemic toxins in haemodialysis (HD) patients
results in increased morbidity and mortality. Whether medium cut-off HD (MCO-HD) …

Aims/hypothesis Microvascular complications are a common feature of diabetes but
additional research is needed regarding diabetic nephropathy endpoints in type 1 and type …

Objective Even though trimethylamine N-oxide (TMAO) has been demonstrated to interfere
with atherosclerosis and diabetes pathophysiology, the association between TMAO and …

OBJECTIVE Renal dysfunction is a key risk factor for all-cause mortality in patients with type
2 diabetes (T2D). Circulating tumor necrosis factor receptor 1 (TNFR1) was recently …

OBJECTIVE Subjects with diabetes are prone to the development of cardiovascular and
noncardiovascular complications. In separate studies, acute kidney injury (AKI), albuminuria …

OBJECTIVE The pattern of renal function decline prior to cardiovascular (CV) events in type
2 diabetes is not well known. Our aim was to describe the association between renal …

OBJECTIVE We explored the prognostic value of three circulating candidate biomarkers—
midregional-proadrenomedullin (MR-proADM), soluble tumor necrosis factor receptor 1 …

Aims/hypothesis A high serum angiopoietin-like 2 (ANGPTL2) concentration is an
independent risk factor for developing diabetes and is associated with insulin resistance and …

Aims The hyperglycaemic stress induces the release of inflammatory proteins such as
S100A12, one of the endogenous ligands of the receptors for advanced glycation end …

No longitudinal data link intraglomerular hemodynamic dysfunction with end-stage kidney
disease (ESKD) in people with type 2 diabetes (T2D). Afferent (RA) and efferent (RE) …