User profiles for "author:Eric J G Sijbrands"

Eric JG Sijbrands

Professor of vascular medicine, Erasmus University Medical Center
Verified email at erasmusmc.nl
Cited by 47660

Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation

GF Watts, S Gidding, AS Wierzbicki, PP Toth… - International journal of …, 2014 - Elsevier
Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth
that markedly elevates plasma low-density lipoprotein (LDL) cholesterol and causes …

Carotid intima-media thickness for cardiovascular risk assessment: systematic review and meta-analysis

SCH van den Oord, EJG Sijbrands, GL ten Kate… - Atherosclerosis, 2013 - Elsevier
OBJECTIVE: B-mode ultrasound measurement of the carotid intima-media thickness (CIMT)
is a widely used marker for atherosclerosis and is associated with future cardiovascular …

Defining severe familial hypercholesterolaemia and the implications for clinical management: a consensus statement from the International Atherosclerosis Society …

RD Santos, SS Gidding, RA Hegele… - The lancet Diabetes & …, 2016 - thelancet.com
Familial hypercholesterolaemia is common in individuals who had a myocardial infarction at
a young age. As many as one in 200 people could have heterozygous familial …

Biological, clinical and population relevance of 95 loci for blood lipids

TM Teslovich, K Musunuru, AV Smith, AC Edmondson… - Nature, 2010 - nature.com
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

[HTML][HTML] Simvastatin with or without ezetimibe in familial hypercholesterolemia

JJP Kastelein, F Akdim, ESG Stroes… - … England Journal of …, 2008 - Mass Medical Soc
Background Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density
lipoprotein (LDL) cholesterol when added to statin treatment. However, the effect of …

Genome-wide association study of blood pressure and hypertension

D Levy, GB Ehret, K Rice, GC Verwoert, LJ Launer… - Nature …, 2009 - nature.com
Blood pressure is a major cardiovascular disease risk factor. To date, few variants
associated with interindividual blood pressure variation have been identified and replicated …

[HTML][HTML] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

YS Aulchenko, S Ripatti, I Lindqvist, D Boomsma… - Nature …, 2009 - ncbi.nlm.nih.gov
Recent genome-wide association (GWA) studies of lipids have been conducted in samples
ascertained for other phenotypes, particularly diabetes. Here we report the first GWA …

High serum uric acid as a novel risk factor for type 2 diabetes

A Dehghan, M Van Hoek, EJG Sijbrands… - Diabetes …, 2008 - Am Diabetes Assoc
OBJECTIVE—To investigate the association between serum uric acid level and risk of type 2
diabetes. RESEARCH DESIGN AND METHODS—The population for analysis consisted of …

Efficacy of statins in familial hypercholesterolaemia: a long term cohort study

J Versmissen, DM Oosterveer, M Yazdanpanah… - Bmj, 2008 - bmj.com
Objective To determine the efficacy of statin treatment on risk of coronary heart disease in
patients with familial hypercholesterolaemia. Design Cohort study with a mean follow-up of …

Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial

A Wiegman, BA Hutten, E De Groot, J Rodenburg… - Jama, 2004 - jamanetwork.com
ContextChildren with familial hypercholesterolemia have endothelial dysfunction and
increased carotid intima-media thickness (IMT), which herald the premature atherosclerotic …