Cardiovascular diseases are the main cause of death in the world and are often associated
with the occurrence of arrhythmias due to disruption of myocardial electrical integrity …

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been used to reduce body
weight in overweight or people with obesity and to improve glycemic control and …

Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent and intractable
form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we …

Myocardial fluid homeostasis relies on a complex interplay between microvascular filtration,
interstitial hydration, cardiomyocyte water uptake and lymphatic removal. Dysregulation of …

The FOXM1 transcription factor exhibits pleiotropic C-terminal transcriptional and N-terminal
non-transcriptional functions in various biological processes critical for cellular homeostasis …

Aim To perform a post hoc analysis of the FIGHT trial, evaluating the effect of liraglutide (vs.
placebo) on the totality of events in patients with heart failure with reduced ejection fraction …

Although pulmonary hypertension (PH) selectively overloads the right ventricle (RV),
neuroendocrine activation and intrinsic myocardial dysfunction have been described in the …

Clinical studies suggest that aerobic exercise can exert beneficial effects in pulmonary
arterial hypertension (PAH), but the underlying mechanisms are largely unknown. We …

OBJECTIVE Patients with type 2 diabetes (T2D) have a high risk for developing heart failure
(HF), which is associated with poor prognosis. Fenofibrate may reduce HF events through …

Aim Glucagon‐like peptide 1 receptor agonists (GLP1‐RA) reduce atherosclerotic events in
patients with type 2 diabetes (T2D) and a high cardiovascular risk. The effect of GLP1‐RA to …