[HTML][HTML] New developments in the diagnosis of dementia

GW Eschweiler, T Leyhe, S Klöppel… - Deutsches Ärzteblatt …, 2010 - ncbi.nlm.nih.gov
Background The terms “dementia” and “Alzheimer's disease” are often wrongly used as if
they were synonyms. Dementia is a clinical syndrome whose main element is memory …

BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls

C Laske, E Stransky, T Leyhe, GW Eschweiler… - Journal of psychiatric …, 2007 - Elsevier
Alzheimer's disease (AD) and normal pressure hydrocephalus (NPH) are common forms of
dementia in the elderly. Recent findings have suggested an involvement of brain-derived …

Antidepressant effects of augmentative transcranial magnetic stimulation: randomised multicentre trial

U Herwig, AJ Fallgatter, J Höppner… - The British Journal of …, 2007 - cambridge.org
BackgroundRepetitive transcranial magnetic stimulation (rTMS) has been proposed as a
new treatment option for depression. Previous studies were performed with low sample …

Impairment of episodic and semantic autobiographical memory in patients with mild cognitive impairment and early Alzheimer's disease

T Leyhe, S Müller, M Milian, GW Eschweiler, R Saur - Neuropsychologia, 2009 - Elsevier
Autobiographical memory includes the retrieval of personal semantic data and the
remembrance of incident or episodic memories. In retrograde amnesias, it has been …

Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression

C Laske, S Banschbach, E Stransky… - International Journal …, 2010 - academic.oup.com
Major depression (MD) has been associated with decreased brain-derived neurotrophic
factor (BDNF) serum levels, while antidepressant drugs were found to increase these …

Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients

C Laske, K Stellos, N Hoffmann… - International Journal …, 2011 - academic.oup.com
The neurotrophin brain-derived neurotrophic factor (BDNF) plays a critical role in neuronal
survival, synaptic plasticity, and memory. Several recent studies have demonstrated altered …

Increase of BDNF serum concentration in lithium treated patients with early Alzheimer's disease

T Leyhe, GW Eschweiler, E Stransky… - Journal of …, 2009 - content.iospress.com
Preclinical and clinical studies gave evidence that lithium could be useful in the treatment of
Alzheimer's disease (AD). In experimental investigations, lithium induces brain-derived …

Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants

C Laske, E Stransky, GW Eschweiler, R Klein… - Journal of psychiatric …, 2007 - Elsevier
Fibromyalgia (FM) is still often viewed as a psychosomatic disorder. However, the increased
pain sensitivity to stimuli in FM patients is not an “imagined” histrionic phenomena. Pain …

[HTML][HTML] Poor trail making test performance is directly associated with altered dual task prioritization in the elderly–baseline results from the TREND study

MA Hobert, R Niebler, SI Meyer, K Brockmann… - PloS one, 2011 - journals.plos.org
Background Deterioration of executive functions in the elderly has been associated with
impairments in walking performance. This may be caused by limited cognitive flexibility and …

Outcomes of a delirium prevention program in older persons after elective surgery: a stepped-wedge cluster randomized clinical trial

F Deeken, A Sánchez, MA Rapp, M Denkinger… - JAMA …, 2022 - jamanetwork.com
Importance Delirium significantly worsens elective surgery outcomes and costs. Delirium risk
is highest in elderly populations, whose surgical health care resource consumption (50%) …